Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

methaphenilene

 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Methapyrilene
analogs & derivativesmethaphenilene hydrochloride

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
1989
1989
S-adenosylmethionine, S-adenosylhomocysteine and DNA methylation levels in the liver of rats fed methapyrilene and analogs.
The antihistamine methapyrilene (hydrochloride) and four close structural analogs, methaphenilene, methafurylene, thenyldiamine… Expand
Is this relevant?
1988
1988
A comparative in vitro metabolic study of methaphenilene and pyribenzamine.
1. In vitro metabolism of methaphenilene (MFN) and pyribenzamine (PBZ) was compared to that of methapyriline (MPH) in rat… Expand
Is this relevant?
1986
1986
Mutagenicity studies of selected antihistamines, their metabolites and products of nitrosation.
Methapyrilene, four structurally related antihistamines, three metabolites of methapyrilene and two products of the reaction of… Expand
Is this relevant?
1986
1986
Carcinogenicity studies of some analogs of the carcinogen methapyrilene in F344 rats
SummaryFour antihistaminic drugs similar in structure to the rat liver carcinogen methapyrilene were administered to comparable… Expand
  • figure 1
  • table 1
  • table 2
Is this relevant?
1985
1985
Carcinogenesis by nonmutagenic chemicals: early response of rat liver cells induced by methapyrilene.
Although methapyrilene (MP) produces hepatocellular carcinomas in rats, it does not elicit many of the cellular responses induced… Expand
  • table 1
Is this relevant?
1984
1984
Mutagenicity of amine drugs and their products of nitrosation.
8 drugs that are amines or amides and that interact with nitrous acid to form potentially carcinogenic and mutagenic N-nitroso… Expand
Is this relevant?
1983
1983
Methaphenilene, an analogue of the antihistaminic methapyrilene, is a “peroxisome proliferator”
The antihistaminic methapyrilene has been identified as a strong hepatocarcinogen in the rat (Lijinsky et al. 1980). In view of… Expand
Is this relevant?
1951
1951
Effect of Histamine and Antihistaminics on Coagulation of Normal and Heparinized Rabbit Plasma
Summary The effects of histamine and a large number of antihistaminic drugs upon the coagulation of normal and heparinized rabbit… Expand
  • table 1
  • figure I
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE