methaphenilene

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1950-1988
0119501988

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1989
1989
The antihistamine methapyrilene (hydrochloride) and four close structural analogs, methaphenilene, methafurylene, thenyldiamine… (More)
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1988
1988
1. In vitro metabolism of methaphenilene (MFN) and pyribenzamine (PBZ) was compared to that of methapyriline (MPH) in rat… (More)
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1986
1986
Four antihistaminic drugs similar in structure to the rat liver carcinogen methapyrilene were administered to comparable groups… (More)
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1986
1986
Methapyrilene, four structurally related antihistamines, three metabolites of methapyrilene and two products of the reaction of… (More)
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1985
1985
Although methapyrilene (MP) produces hepatocellular carcinomas in rats, it does not elicit many of the cellular responses induced… (More)
  • table 1
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1984
1984
8 drugs that are amines or amides and that interact with nitrous acid to form potentially carcinogenic and mutagenic N-nitroso… (More)
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1983
1983
The antihistaminic methapyrilene has been identified as a strong hepatocarcinogen in the rat (Lijinsky et al. 1980). In view of… (More)
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1950
1950
 
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