methaphenilene
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
The antihistaminic methapyrilene has been identified as a strong hepatocarcinogen in the rat (Lijinsky et al. 1980). In view of…
SummaryFour antihistaminic drugs similar in structure to the rat liver carcinogen methapyrilene were administered to comparable…
The antihistamine methapyrilene (hydrochloride) and four close structural analogs, methaphenilene, methafurylene, thenyldiamine…
1. In vitro metabolism of methaphenilene (MFN) and pyribenzamine (PBZ) was compared to that of methapyriline (MPH) in rat…
Although methapyrilene (MP) produces hepatocellular carcinomas in rats, it does not elicit many of the cellular responses induced…
Summary The effects of histamine and a large number of antihistaminic drugs upon the coagulation of normal and heparinized rabbit…