methanethiosulfonate ethylammonium

Known as: AEMTS cpd, methanethiosulfonate ethylamine, MTSEA 
 
National Institutes of Health

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Ethyl MethanesulfonateIndicators and Reagents
analogs & derivatives

Papers overview

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Highly Cited
2007
Highly Cited
2007
Noxious compounds activate TRPA1 ion channels through covalent modification of cysteines
The nervous system senses peripheral damage through nociceptive neurons that transmit a pain signal. TRPA1 is a member of the… (More)
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2007
2007
Cysteine substitution mutants give structural insight and identify ATP binding and activation sites at P2X receptors.
P2X receptors for extracellular ATP are a distinct family of ligand-gated cation channels involved in physiological processes… (More)
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2003
2003
Methanethiosulfonate ethylammonium block of amine currents through the ryanodine receptor reveals single pore architecture.
The homotetrameric structure of the ryanodine-sensitive intracellular calcium (Ca2+) release channel (ryanodine receptor (RyR… (More)
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Highly Cited
2002
Highly Cited
2002
Conserved cysteine residues in the extracellular loop of the human P2X(1) receptor form disulfide bonds and are involved in receptor trafficking to the cell surface.
P2X receptors contain 10 conserved cysteines in the extracellular loop. To investigate whether these residues form disulfide… (More)
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Highly Cited
2001
Highly Cited
2001
Structure and dynamics of the GABA binding pocket: A narrowing cleft that constricts during activation.
Photo-affinity labeling and mutagenesis studies have identified several amino acids that may contribute to the ligand binding… (More)
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Highly Cited
2000
Highly Cited
2000
Immobilizing the Moving Parts of Voltage-Gated Ion Channels
Voltage-gated ion channels have at least two classes of moving parts, voltage sensors that respond to changes in the… (More)
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Highly Cited
2000
Highly Cited
2000
Oligomerization of serotonin transporter and its functional consequences.
Two forms of serotonin transporter (SERT) were prepared with different epitope tags. When co-expressed in HeLa cells, the form… (More)
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1999
1999
Modulation of recombinant human cardiac L-type Ca2+ channel alpha1C subunits by redox agents and hypoxia.
1. Whole-cell patch clamp recordings were used to investigate the modulation by reducing and oxidizing agents of recombinant… (More)
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Highly Cited
1998
Highly Cited
1998
A domain contributing to the ion channel of ATP-gated P2X2 receptors identified by the substituted cysteine accessibility method.
P2X receptors are a family of ATP-gated ion channels thought to have intracellular N and C termini and two transmembrane segments… (More)
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1998
1998
A Reentrant Loop Domain in the Glutamate Carrier EAAT1 Participates in Substrate Binding and Translocation
To investigate the structural determinants underlying transport by the glutamate transporter EAAT1, we mutated each of 24 highly… (More)
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