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methacetin

Known as: N-(4-methoxyphenyl)acetamide 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Acetamides

Narrower (1)

methacetin, 14C-labeled

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2009
2009
Point-of-care continuous (13)C-methacetin breath test improves decision making in acute liver disease: results of a pilot clinical trial.
AIM To assess the role of the (13)C-methacetin breath test (MBT) in patients with acute liver disease. METHODS Fifteen patients… Expand
Highly Cited
2008
Highly Cited
2008
A continuous 13C methacetin breath test for noninvasive assessment of intrahepatic inflammation and fibrosis in patients with chronic HCV infection and normal ALT
Summary.  Up to 30% of patients with hepatitis C virus (HCV) infection and normal serum alanine aminotransferase (NALT) have… Expand
Review
2007
Review
2007
Review article: the assessment of liver function using breath tests
  • Y. Ilan
  • Alimentary pharmacology & therapeutics
  • 2007
    • Corpus ID: 11751899
Background  Hepatologists have long sought to develop a test for assessing liver function, but this aim has been stalled by the… Expand
Highly Cited
2005
Highly Cited
2005
[13C]methacetin breath test for evaluation of liver damage
Methacetin undergoes rapid O-dealkylation by hepatic microsomal enzyme systems, and the resultant CO2 is present in the expired… Expand
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Highly Cited
2005
Highly Cited
2005
Measurement of hepatic functional mass by means of 13C-methacetin and 13C-phenylalanine breath tests in chronic liver disease: comparison with Child-Pugh score and serum bile acid levels.
AIM To evaluate and compare the clinical usefulness of 13C-phenylalanine and 13C-methacetin breath tests in quantitating… Expand
Highly Cited
2004
Highly Cited
2004
In vitro activity of commercial valerian root extracts against human cytochrome P450 3A4.
PURPOSE Valerian root ( Valeriana officinalis L.) has been used since antiquity as a medicinal herb. Recent studies have found… Expand
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2004
2004
Nuclear medicine liver function tests for pregnant women and children 1. Breath tests with 14C-methacetin and 13C-methacetin
Stable isotopes, such as 13C, should be substituted for the long-lived radionuclide 14C in the 14C breath test when doing liver… Expand
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Highly Cited
2004
Highly Cited
2004
Rate-limiting steps in oxidations catalyzed by rabbit cytochrome P450 1A2.
Several issues regarding the rate-limiting nature of individual reaction steps in catalysis by rabbit liver cytochrome P450 (P450… Expand
Highly Cited
2003
Highly Cited
2003
13C‐methacetin breath test for monitoring hepatic function in cirrhotic patients before and after liver transplantation
Background : In patients with chronic liver disease, the measurement of liver function is critical for monitoring disease… Expand
Highly Cited
1997
Highly Cited
1997
Evaluation of the 13C-methacetin breath test for quantitative liver function testing.
Noninvasive 13C-breath tests are used for the assessment of hepatocellular dysfunction. 13C-methacetin is metabolized in the… Expand
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