methacetin

BACKGROUND AND AIM Distinguishing biliary atresia (BA) from other causes of neonatal cholestasis (NC) is challenging. Continuous… (More)

AIM To find the most reproducible quantitative parameter of a standard (13)C-methacetin breath test ((13)C-MBT). METHODS Twenty… (More)

It is essential to establish whether and how environmental factors affect the reliability of [(13)C]methacetin breath test ((13)C… (More)

BACKGROUND AND AIM Methacetin is thought to be a good substrate for the evaluation of different cytochrome P450 enzymatic systems… (More)

SUMMARY Up to 30% of patients with hepatitis C virus (HCV) infection and normal serum alanine aminotransferase (NALT) have… (More)

AIM To evaluate and compare the clinical usefulness of 13C-phenylalanine and 13C-methacetin breath tests in quantitating… (More)

BACKGROUND Hypoxia may contribute to impairment of liver function and thus interfere with results of liver tests. In patients… (More)

BACKGROUND To grade liver damage, Child-Pugh classification is used but these tests do not reflect the quantitative functional… (More)

Noninvasive 13C-breath tests are used for the assessment of hepatocellular dysfunction. 13C-methacetin is metabolized in the… (More)

Methacetin undergoes rapid O-dealkylation by hepatic microsomal enzyme systems, and the resultant CO2 is present in the expired… (More)