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Regulation of the sodium bicarbonate cotransporter knbc1 function: role of Asp986, Asp988 and kNBC1‐carbonic anhydrase II binding
The HCO3− : Na+ cotransport stoichiometry of the electrogenic sodium bicarbonate cotransporter kNBC1 determines the reversal potential (Erev) and thus the net direction of transport of these ionsExpand
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Older children and adolescents living with perinatally acquired human immunodeficiency virus infection.
OBJECTIVE To describe the clinical, immunologic, and psychosocial characteristics of children living with perinatally-acquired human immunodeficiency virus (HIV) infection beyond the age of 9 years.Expand
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Structural determinants and significance of regulation of electrogenic Na(+)-HCO(3)(-) cotransporter stoichiometry.
  • E. Gross, I. Kurtz
  • Chemistry, Medicine
  • American journal of physiology. Renal physiology
  • 1 November 2002
Na(+)-HCO(3)(-) cotransporters play an important role in intracellular pH regulation and transepithelial HCO(3)(-) transport in various tissues. Of the characterized members of the HCO(3)(-)Expand
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Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras
IN the yeast Sacchromyces cerevisiae, addition of glucose to starved cells triggers a transient rise in the intracellular level of cyclic AMP that induces a protein phosphorylation cascade1. TheExpand
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Functional characterization of NBC4: a new electrogenic sodium-bicarbonate cotransporter.
Sodium-bicarbonate cotransporters are homologous membrane proteins mediating the electrogenic or electroneutral transport of sodium and bicarbonate. Of the functionally characterizedExpand
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Phosphorylation‐Induced Modulation of pNBC1 Function: Distinct Roles for the Amino‐ and Carboxy‐Termini
The human NBC1 (SLC4A4) gene encodes the electrogenic sodium bicarbonate cotransporters kNBC1 and pNBC1, which are highly expressed in the kidney and pancreas, respectively. The HCO3−:Na+Expand
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Molecular mechanism of kNBC1–carbonic anhydrase II interaction in proximal tubule cells
We have recently shown that carbonic anhydrase II (CAII) binds in vitro to the C‐terminus of the electrogenic sodium bicarbonate cotransporter kNBC1 (kNBC1‐ct). In the present study we determined theExpand
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Tyrosine Modification Is Not Required for Myeloperoxidase-induced Loss of Apolipoprotein A-I Functional Activities*
Apolipoprotein A-I (apoAI), the major protein of high density lipoprotein, plays an important role in reverse cholesterol transport via its activity as an ABCA1-dependent acceptor of cellularExpand
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Voltage and cosubstrate dependence of the Na-HCO3 cotransporter kinetics in renal proximal tubule cells.
The voltage dependence of the kinetics of the sodium bicarbonate cotransporter was studied in proximal tubule cells. This electrogenic cotransporter transports one Na+, three HCO3-, and two negativeExpand
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Gastric Transposition for Esophageal Replacement in Children: Experience With 41 Consecutive Cases With Special Emphasis on Esophageal Atresia
ObjectiveTo evaluate the authors’ experience with gastric transposition as a method of esophageal replacement in children with congenital or acquired abnormalities of the esophagus. SummaryExpand
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