metallopeptidase activity

Known as: metalloprotease activity, metalloproteinase activity 
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in… (More)
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
BACKGROUND Atherosclerotic lesions are predominantly observed in curved arteries and near side branches, where low or oscillatory… (More)
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Highly Cited
2004
Highly Cited
2004
Therapeutic plasma exchange is an effective empiric treatment for thrombotic thrombocytopenic purpura (TTP), but how therapy… (More)
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Highly Cited
2001
Highly Cited
2001
Oxidative stress has been implicated in the pathophysiology of myocardial failure. We tested the hypothesis that oxidative stress… (More)
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Highly Cited
2001
Highly Cited
2001
Diabetes mellitus (DM) is a primary risk factor for cardiovascular disease. Although recent studies have demonstrated an… (More)
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Highly Cited
2000
Highly Cited
2000
Targeted ablation of the surfactant protein D (SP-D) gene caused chronic inflammation, emphysema, and fibrosis in the lungs of SP… (More)
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Highly Cited
1999
Highly Cited
1999
To assess the differences in proteolytic activity of acute and chronic wound environments, wound fluids were collected from acute… (More)
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Highly Cited
1998
Highly Cited
1998
BACKGROUND Proteolytic enzyme activity in lipid-rich atheroma may promote plaque rupture and precipitate acute coronary syndromes… (More)
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Highly Cited
1996
Highly Cited
1996
Smooth muscle cell (SMC) migration and replication are important for neointimal formation after arterial injury. Migration of… (More)
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Highly Cited
1995
Highly Cited
1995
Nitric oxide (NO.) is a multifunctional messenger molecule generated by a family of enzymes, collectively termed the nitric oxide… (More)
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Highly Cited
1992
Highly Cited
1992
The balance between levels of metalloproteinases and their corresponding inhibitors is a critical factor in tumor invasion and… (More)
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