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metal transporting protein 1

Known as: ferroportin, ferroportin1 protein, solute carrier family 40 (iron-regulated transporter), member 1 
National Institutes of Health

Related topics

Related topics

3 relations

Broader (1)

Cation Transport Proteins
SLC40A1 gene

Narrower (1)

SLC40A1 protein, human

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2014
Review
2014
Iron at the interface of immunity and infection
Both, mammalian cells and microbes have an essential need for iron, which is required for many metabolic processes and for… 
Review
2013
Review
2013
Role of hepcidin in the pathophysiology and diagnosis of anemia
This review summarizes the central role of hepcidin in the iron homeostasis mechanism, the molecular mechanism that can alter… 
Review
2012
Review
2012
The metal theory of Alzheimer's disease.
Brain homeostasis of transition metals is severely perturbed in Alzheimer's disease (AD), with extracellular pooling of zinc and… 
Highly Cited
2012
Highly Cited
2012
Hypoxia-inducible factor regulates hepcidin via erythropoietin-induced erythropoiesis.
Iron demand in bone marrow increases when erythropoiesis is stimulated by hypoxia via increased erythropoietin (EPO) synthesis in… 
Review
2007
Review
2007
Molecular control of iron transport.
The iron-regulatory hormone hepcidin is a 25-amino acid peptide that is synthesized in hepatocytes. Hepcidin binds to the… 
Review
2006
Review
2006
Iron imports. IV. Hepcidin and regulation of body iron metabolism.
  • T. GanzE. Nemeth
  • American Journal of Physiology - Gastrointestinal…
  • 2006
  • Corpus ID: 11769602
Hepcidin, a small peptide synthesized in the liver, controls extracellular iron by regulating its intestinal absorption… 
Highly Cited
2006
Highly Cited
2006
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Progressive iron overload is the most salient and ultimately fatal complication of beta-thalassemia. However, little is known… 
Review
2006
Review
2006
Hepcidin and its role in regulating systemic iron metabolism.
  • T. Ganz
  • Hematology. American Society of Hematology…
  • 2006
  • Corpus ID: 13286751
Maintenance of stable extracellular iron concentrations requires the coordinate regulation of iron transport into plasma from… 
Highly Cited
2005
Highly Cited
2005
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin.
Ferroportin 1 (FPN1) is transmembrane protein involved in iron homeostasis. In the duodenum, FPN1 localizes to the basolateral… 
Highly Cited
2005
Highly Cited
2005
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
Iron homeostasis plays a critical role in many physiological processes, notably synthesis of heme proteins. Dietary iron sensing… 
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