Skip to search formSkip to main contentSkip to account menu

SLC40A1 gene

Known as: solute carrier family 40 member 1, IREG1, FERROPORTIN 1 
National Institutes of Health

Related topics

Related topics

3 relations
HEMOCHROMATOSIS, TYPE 4SLC40A1 protein, humanmetal transporting protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2006
Highly Cited
2006
Ineffective erythropoiesis in beta-thalassemia is characterized by increased iron absorption mediated by down-regulation of hepcidin and up-regulation of ferroportin.
Progressive iron overload is the most salient and ultimately fatal complication of beta-thalassemia. However, little is known… 
Highly Cited
2006
Highly Cited
2006
Hepcidin expression and iron transport in alveolar macrophages.
Alveolar macrophages express many proteins important in iron homeostasis, including the iron importer divalent metal transport 1… 
Highly Cited
2005
Highly Cited
2005
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin.
Ferroportin 1 (FPN1) is transmembrane protein involved in iron homeostasis. In the duodenum, FPN1 localizes to the basolateral… 
Review
2005
Review
2005
Iron imports. I. Intestinal iron absorption and its regulation.
Our knowledge of how the body absorbs iron from the diet and how this process is controlled has increased at a rapid rate in… 
Highly Cited
2003
Highly Cited
2003
Disrupted hepcidin regulation in HFE-associated haemochromatosis and the liver as a regulator of body iron homoeostasis
Review
2003
Review
2003
Iron Metabolism in the Reticuloendothelial System
Comprised mainly of monocytes and tissue macrophages, the reticuloendothelial system (RES) plays two major roles in iron… 
Highly Cited
2002
Highly Cited
2002
Mechanisms of iron mediated regulation of the duodenal iron transporters divalent metal transporter 1 and ferroportin 1.
Intestinal iron absorption is regulated by the body's demands for iron. Identification of divalent metal transporter 1 (DMT1) and… 
Highly Cited
2002
Highly Cited
2002
A valine deletion of ferroportin 1: a common mutation in hemochromastosis type 4.
Hemochromatosis type 4 is an atypical hemochromatosis characterized by dominant inheritance, increased serum ferritin, normal… 
Highly Cited
2002
Highly Cited
2002
Duodenal mRNA expression of iron related genes in response to iron loading and iron deficiency in four strains of mice
Background: Although much progress has been made recently in characterising the proteins involved in duodenal iron trafficking… 
Highly Cited
2001
Highly Cited
2001
Zinc regulates the function and expression of the iron transporters DMT1 and IREG1 in human intestinal Caco‐2 cells
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)