mespirenone

Known as: 7alpha-acetylthio-15beta,16beta-methylene-3-oxo-17alpha-pregna-1,4-diene-21,17-carbolactone

A spironolactone derivative and aldosterone antagonist with diuretic activity. Mespirenone, after in vivo metabolization, inhibits aldosterone…

National Institutes of Health

Papers overview

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1990

A dissertation in partial fulfillment of the requirements for the degree of Doctor of Philosophy at the Virginia Commonwealth…

1987

Some 15,16-methylene derivatives of the aldosterone antagonist spironolactone were synthesized with the purpose of increasing the…

1986