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medermycin

Known as: lactoquinomycin 
National Institutes of Health

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1 relation

Broader (1)

Naphthoquinones

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
A new medermycin analog from the marine-derived actinomycetes Streptomyces sp. ZS-A45
Abstract A new medermycin analog (1) was isolated from the marine-derived actinomycetes Streptomyces sp. ZS-A45. The structure… 
2015
2015
Studies towards the synthesis of medermycin via Dötz benzannulation.
The C-arylglycosides are available in enantiomerically pure form via the Dötz benzannulation reaction between Fischer alkenyl… 
2014
2014
Genome sequencing and annotation of Amycolatopsis azurea DSM 43854T
2012
2012
[Expression detection of med-ORF12 encoding a stereochemical ketoreductase possibly involved in medermycin biosynthesis].
UNLABELLED Medermycin, an aromatic polyketide antibiotic produced by streptomyces, possesses a stereochemical-pyran-ring lactone… 
2010
2010
Practical procedures for genetic manipulation systems for medermycin‐producing Streptomyces sp. AM‐7161
Streptomyces sp. AM‐7161 is a producer of an aromatic polyketide medermycin with strong antibacterial and antitumor activity. It… 
Highly Cited
2007
Highly Cited
2007
Discovery of lactoquinomycin and related pyranonaphthoquinones as potent and allosteric inhibitors of AKT/PKB: mechanistic involvement of AKT catalytic activation loop cysteines
The serine/threonine kinase AKT/PKB plays a critical role in cancer and represents a rational target for therapy. Although… 
2003
2003
Synthesis of 3-azido-2,3,6-trideoxy-beta-D-arabino-hexopyranosyl pyranonaphthoquinone analogues of medermycin.
The synthesis of an isomeric mixture of 4-O-acetyl-3-azido-2,3,6-trideoxy-beta-D-arabino-hexopyranosyl analogues 6 of the C… 
1987
1987
Inhibition of platelet aggregation by medermycin and it's related isochromanequinone antibiotics.
1986
1986
Lactoquinomycin B, a novel antibiotic.
Streptomyces tanashiensis IM8442T was found to produce lactoquinomycin B, a novel antibiotic, together with lactoquinomycin A… 
1985
1985
Lactoquinomycin, a novel anticancer antibiotic. I. Taxonomy, isolation and biological activity.
Lactoquinomycin, a novel basic antibiotic, was isolated from the culture broth of a soil streptomyces by repeated solvent… 
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