mdm2 protein

Known as: Proto Oncogene Proteins c mdm2, c mdm2 Proto Oncogene Protein, c-mdm2 Proto-Oncogene Protein 
An E3 UBIQUITIN LIGASE that interacts with and inhibits TUMOR SUPPRESSOR PROTEIN P53. Its ability to ubiquitinate p53 is regulated by TUMOR… (More)
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2013
Highly Cited
2013
Dysregulated microRNAs (miRNAs) have an important role in many malignant tumors. However, elucidating the roles of miRNAs in… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2013
2013
Allelic deletion of the RPS14 gene is a key effector of the hypoplastic anemia in patients with myelodysplastic syndrome (MDS… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
2008
2008
The mechanisms underlying blood-brain barrier (BBB) dysfunction seen in human immunodeficiency virus 1 (HIV-1) infection are… (More)
Is this relevant?
Highly Cited
2007
Highly Cited
2007
A paper by Bond et al. reported that a single-nucleotide polymorphism (SNP) in the intronic promoter region of the mouse double… (More)
  • table I
  • table I
  • figure 1
Is this relevant?
2005
2005
Cognitive, behavioral, and motor impairments, during progressive human immunodeficiency virus type 1 (HIV-1) infection, are… (More)
  • figure 1
  • table 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
2003
2003
Oncoprotein Mdm2 is a master negative regulator of the tumor suppressor p53 and has been recently shown to regulate the… (More)
Is this relevant?
2001
2001
Regulation of p53 involves a complex network of protein interactions. The primary regulator of p53 protein stability is the Mdm2… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The p53 protein can bind to a set of specific DNA sequences, and this may activate the transcription of genes adjacent to these… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
The 90-kDa cellular protein encoded by the mouse mdm-2 oncogene binds to the p53 protein in vivo and inhibits its transactivation… (More)
Is this relevant?
Highly Cited
1993
Highly Cited
1993
A protein product of the mdm-2 oncogene (p90) has been recently shown to associate with the protein encoded by the tumor… (More)
Is this relevant?