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maraviroc

Known as: 4,4-difluoro-N-((1S)-3-(exo-3-(3-isopropyl-5-methyl-4H-1,2,4-triazol-4-yl)-8-azabicyclo(3.2.1)oct-8-yl)-1-phenylpropyl)cyclohexanecarboxamide, maraviroc [Chemical/Ingredient] 
A C-C Chemokine Receptor Type 5 (CCR5) antagonist with activity against human immunodeficiency virus (HIV). Maraviroc inhibits HIV-1 entry via CCR5… Expand
National Institutes of Health

Papers overview

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Review
2017
Review
2017
Purpose of ReviewThis review focuses on the differential effects of contemporary antiretrovirals on systemic inflammation as… Expand
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Review
2015
Review
2015
Inflammation is one of the most characteristic features of chronic liver disease of viral, alcoholic, fatty, and autoimmune… Expand
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Highly Cited
2013
Highly Cited
2013
The CCR5 chemokine receptor acts as a co-receptor for HIV-1 viral entry. Here we report the 2.7 angstrom-resolution crystal… Expand
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Highly Cited
2011
Highly Cited
2011
BACKGROUND Deep sequencing is a highly sensitive technique that can detect and quantify the proportion of non-R5 human… Expand
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Highly Cited
2010
Highly Cited
2010
An effective vaginal microbicide could reduce human immunodeficiency virus type 1 (HIV-1) transmission to women. Among… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND CC chemokine receptor 5 antagonists are a new class of antiretroviral agents. METHODS We conducted two double-blind… Expand
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Highly Cited
2008
Highly Cited
2008
BACKGROUND We conducted subanalyses of the combined results of the Maraviroc versus Optimized Therapy in Viremic Antiretroviral… Expand
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Highly Cited
2007
Highly Cited
2007
Maraviroc is a CCR5 antagonist in clinical development as one of a new class of antiretrovirals targeting human immunodeficiency… Expand
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Highly Cited
2005
Highly Cited
2005
Maraviroc (UK-427,857) is a selective CCR5 antagonist with potent anti-human immunodeficiency virus type 1 (HIV-1) activity and… Expand
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Highly Cited
2005
Highly Cited
2005
We assessed the efficacy and safety of 10-d monotherapy with the orally administered CCR5 antagonist maraviroc in 63 HIV-1… Expand
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