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CCR5 Receptor Antagonists

Known as: CCR5 Receptor Blockers, Receptor Antagonists, CCR5, Blockers, CCR5 Receptor 
Compounds and drugs that inhibit or block the activity of CCR5 RECEPTORS.
National Institutes of Health

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GSK 163929PF 232798RO-5657TAK 779
In Bloodaspects of radiation effectschemical synthesisstandards characteristics

Papers overview

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2017
2017
Comprehensive Cross-Clade Characterization of Antibody-Mediated Recognition, Complement-Mediated Lysis, and Cell-Mediated Cytotoxicity of HIV-1 Envelope-Specific Antibodies toward Eradication of the…
ABSTRACT Immunotherapy with passive administration of broadly neutralizing HIV-1 envelope-specific antibodies (bnAbs) in the… 
2015
2015
Synthesis, binding affinity and structure-activity relationships of novel, selective and dual targeting CCR2 and CCR5 receptor antagonists.
CCR2 and CCR5 receptors play a key role in the development and progression of several inflammatory, cardiovascular and autoimmune… 
2014
2014
Chemokine receptor 5 (CCR5) delta 32 polymorphism in lupus nephritis: A large case-control study and meta-analysis
Abstract Objectives: Recent animal experiments showed that CCR5-deficient lupus mice (CCR5−/−) were closely associated with… 
Review
2009
Review
2009
Role of CCR5 Δ32 bp deletion in RA and SLE
CCR5 and its ligands play important roles in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). A deletion of 32… 
2008
2008
CCR5-Delta32 polymorphism and susceptibility to cervical cancer: association with early stage of cervical cancer.
Inflammation plays a major role in the pathogenesis of cervical cancer. Chemokines are involved in inflammation, cancer, and… 
2008
2008
Engineered CCR5 superagonist chemokine as adjuvant in anti-tumor DNA vaccination.
2008
2008
Effect of CCR5 receptor antagonists on endocytosis of the human CCR5 receptor in CHO‐K1 cells
The CCR5 chemokine receptor is a member of the G protein‐coupled receptor (GPCR) family that is expressed by macrophages, memory… 
Review
2003
Review
2003
Population Survey of CCR5 &Dgr;32, CCR5 m303, CCR2b 64I, and SDF1 3´A Allele Frequencies in Indigenous Chinese Healthy Individuals, and in HIV-1-Infected and HIV-1-Uninfected Individuals in HIV-1…
The aim of this study is to determine in indigenous Chinese ethnic groups the frequencies of the chemokine (SDF1 3´A) and… 
2003
2003
Relative importance of CCR5 and antineutrophil cytoplasmic antibodies in patients with Wegener's granulomatosis.
OBJECTIVE Wegener's granulomatosis (WG) is an idiopathic inflammatory condition characterized by upper and lower airway… 
2000
2000
Causal Pathways for CCR5 Genotype and HIV Progression
Summary: A homozygous 32‐bp deletion in the gene encoding CCR5, a major coreceptor for HIV‐1, leads to resistance to infection… 
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