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mannostatin A

Known as: 1,2,3-Cyclopentanetriol, 4-amino-5-(methylthio)-, 4-amino-5-methylthio-1,2,3-cyclopentanetriol 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Cyclopentanes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Toward a Stereoselective Synthesis of Tetrahydroxy Long Chain Base (LCB) and the Synthesis of Analogues of Mannostatin A.
Aldehyde (VI), a possible intermediate in the synthesis of LCB (VII), is prepared via a diastereoselective reduction of ketone (I… 
2009
2009
The Molecular Basis of Inhibition of Golgi α‐Mannosidase II by Mannostatin A
Mannostatin A is a potent inhibitor of the mannose‐trimming enzyme, Golgi α‐mannosidase II (GMII), which acts late in the N… 
Highly Cited
2006
Highly Cited
2006
Structural basis of the inhibition of Golgi alpha-mannosidase II by mannostatin A and the role of the thiomethyl moiety in ligand-protein interactions.
The X-ray crystal structures of mannose trimming enzyme drosophila Golgi alpha-mannosidase II (dGMII) complexed with the… 
2000
2000
Synthesis of a potent aminocyclitol alpha-mannosidase inhibitor, 1L-(1,2,3,5/4)-5-amino-4-O-methyl-1,2,3,4-cyclopentanetetrol.
1999
1999
Synthesis and biological evaluation of α-mannosidase inhibitory activity of three deoxy derivatives of mannostatin A
1996
1996
Flexible Enantiodivergent Synthesis and Biological Activity of Mannostatin Analogues, New Cyclitol Glycosidase Inhibitors.
Mannostatin A (1) is a new cyclitol inhibitor of glycoprotein processing. 2-Epimannostatin A (12) and its enantiomer (13) as well… 
1992
1992
新規酵素阻害剤 Mannostatin A の全合成
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