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maleylacetone

National Institutes of Health

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AcetoneMaleates
analogs & derivatives

Papers overview

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2019
2019
Mitochondrial Glutathione Transferase Zeta 1 is Inactivated More Rapidly by Dichloroacetate than the Cytosolic Enzyme in Adult and Juvenile Rat Liver.
Dichloroacetate (DCA) has potential for treating mitochondrial disorders and cancer by activating the mitochondrial pyruvate… 
2015
2015
Haplotype variations in glutathione transferase zeta 1 influence the kinetics and dynamics of chronic dichloroacetate in children
Dichloroacetate (DCA) is biotransformed by glutathione transferase zeta 1 (GSTZ1), a bifunctional enzyme that, as… 
2009
2009
Phenylalanine-induced leucopenia in genetic and dichloroacetic acid generated deficiency of glutathione transferase Zeta.
2005
2005
INACTIVATION OF GLUTATHIONE S TRANSFERASE ZETA BY DICHLOROACETIC ACID
of Dissertation Presented to the Graduate School of the University of Florida in Partial Fulfillment of the Requirements for the… 
2003
2003
Perturbation of maleylacetoacetic acid metabolism in rats with dichloroacetic Acid-induced glutathione transferase zeta deficiency.
Glutathione transferase zeta (GSTZ1-1) catalyzes the isomerization of maleylacetoacetate (MAA) to fumarylacetoacetate, the… 
2002
2002
Kinetics of the biotransformation of maleylacetone and chlorofluoroacetic acid by polymorphic variants of human glutathione transferase zeta (hGSTZ1-1).
Glutathione transferase zeta (GSTZ1-1) catalyzes the cis-trans isomerization of maleylacetoacetate and the biotransformation of a… 
2001
2001
Inactivation of polymorphic variants of human glutathione transferase zeta (hGSTZ1-1) by maleylacetone and fumarylacetone.
Glutathione transferase zeta (GSTZ1-1), 1 which is identical to maleylacetoacetate isomerase (EC 5.2.1.2) 2 is the penultimate… 
1989
1989
cis-beta-acetylacrylate is a substrate for maleylacetoacetate cis-trans isomerase. Mechanistic implications.
Maleylacetoacetate cis-trans isomerase together with coenzyme glutathione catalyzes cis-trans isomerization of cis-beta… 
1976
1976
Maleylacetone cis-trans-isomerase: affinity chromatography on glutathione-bound sepharose. Two-substrate-binding sequence from inhibition patterns.
Maleylacetone cis-trans-isomerase isolated from Vibrio 01 binds glutathione strongly; Km = 1.4 X 10(-4) M. Oxidized glutathione… 
1973
1973
Purification and properties of maleylacetone cis-trans isomerase from vibrio 01.
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