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macrophage stimulatory lipopeptide 2

Known as: MALP-2, S-(2,3-bispalmitoyloxypropyl)-CGNNDESNISFKEK 
National Institutes of Health

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Lipopeptides

Papers overview

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2016
2016
Macrophage-activating lipopeptide-2 downregulates the expression of ATP-binding cassette transporter A1 by activating the TLR2/NF-кB/ZNF202 pathway in THP-1 macrophages.
Macrophage-activating lipopeptide-2 (MALP-2) has been shown to promote the development of atherosclerosis. ATP-binding cassette… 
2013
2013
Toll-Like Receptor 2/6 Agonist Macrophage-Activating Lipopeptide-2 Promotes Reendothelialization and Inhibits Neointima Formation After Vascular Injury
Objective—Reendothelialization after vascular injury (ie, balloon angioplasty or stent implantation) is clinically extremely… 
2010
2010
Human monocytes tolerant to LPS retain the ability to phagocytose bacteria and generate reactive oxygen species.
Tolerance to lipopolysaccharide (LPS) occurs when animals or cells exposed to LPS become hyporesponsive to a subsequent challenge… 
2009
2009
The Toll-like Receptor 2/6 Ligand MALP-2 Reduces the Viability of Mycobacterium tuberculosis in Murine Macrophages
Toll-like receptors (TLRs) sense conserved structures of pathogens and influence macrophage functions. Here we investigated the… 
Highly Cited
2008
Highly Cited
2008
Prime-boost immunization with cruzipain co-administered with MALP-2 triggers a protective immune response able to decrease parasite burden and tissue injury in an experimental Trypanosoma cruzi…
Highly Cited
2007
Highly Cited
2007
Intratumoural injection of the toll-like receptor-2/6 agonist ‘macrophage-activating lipopeptide-2’ in patients with pancreatic carcinoma: a phase I/II trial
This phase I/II trial examined safety and efficacy of the toll-like receptor 2/6 agonist MALP-2 in combination with gemcitabine… 
2007
2007
Fibrin as a delivery vehicle for active macrophage activator lipoprotein‐2 peptide: in vitro studies
Fibrin sealants have been used in hemostasis and tissue sealing for over 25 years and recent studies have shown them to be an… 
2004
2004
The Mycoplasma-Derived Macrophage-Activating 2-Kilodalton Lipopeptide Triggers Global Immune Activation on Nasal Mucosa-Associated Lymphoid Tissues
ABSTRACT A better knowledge on how immune responses are initiated in mucosal tissues would facilitate the design of new mucosal… 
Highly Cited
2000
Highly Cited
2000
MALP-2, a Mycoplasma lipopeptide with classical endotoxic properties: end of an era of LPS monopoly?
Although some activities of LPS are shared by other bacterial components, for half a century LPS has been regarded as unique in… 
1999
1999
Effect of MALP-2, a Lipopeptide fromMycoplasma fermentans, on Bone Resorption In Vitro
ABSTRACT Mycoplasmas may be associated with rheumatoid arthritis in various animal hosts. In humans, mycoplasma arthritis has… 
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