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macroautophagy

Known as: autophagy in response to cellular starvation, non-specific autophagy, starvation-induced autophagy 
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of… Expand
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Selective macroautophagy is an important protective mechanism against diverse cellular stresses. In contrast to the well… Expand
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Highly Cited
2014
Highly Cited
2014
Significance The normal function of the Huntingtin (HTT) protein is emerging. Here we report that selective autophagy requires an… Expand
Highly Cited
2010
Highly Cited
2010
Starvation-induced autophagosomes engulf cytosol and/or organelles and deliver them to lysosomes for degradation, thereby… Expand
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Highly Cited
2009
Highly Cited
2009
The Hsc/Hsp70 co‐chaperones of the BAG (Bcl‐2‐associated athanogene) protein family are modulators of protein quality control. We… Expand
Highly Cited
2008
Highly Cited
2008
Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by… Expand
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Review
2008
Review
2008
  • E. Eskelinen
  • International review of cell and molecular…
  • 2008
  • Corpus ID: 26874033
Macroautophagy is a self-digesting pathway responsible for the removal of long-lived proteins and organelles by the lysosomal… Expand
Highly Cited
2008
Highly Cited
2008
Autophagy induced by nutrient depletion is involved in survival during starvation conditions. In addition to starvation-induced… Expand
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Highly Cited
2007
Highly Cited
2007
The anti‐apoptotic proteins Bcl‐2 and Bcl‐XL bind and inhibit Beclin‐1, an essential mediator of autophagy. Here, we demonstrate… Expand
Review
2006
Review
2006
Macroautophagy, a lysosomal pathway responsible for the turnover of organelles and long-lived proteins, has been regarded mainly… Expand
Highly Cited
2005
Highly Cited
2005
During starvation-induced autophagy in mammals, autophagosomes form and fuse with lysosomes, leading to the degradation of the… Expand