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Selective macroautophagy is an important protective mechanism against diverse cellular stresses. In contrast to the well… Expand Significance The normal function of the Huntingtin (HTT) protein is emerging. Here we report that selective autophagy requires an… Expand Starvation-induced autophagosomes engulf cytosol and/or organelles and deliver them to lysosomes for degradation, thereby… Expand The Hsc/Hsp70 co‐chaperones of the BAG (Bcl‐2‐associated athanogene) protein family are modulators of protein quality control. We… Expand Starvation induces autophagy to preserve cellular homeostasis in virtually all eukaryotic organisms. However, the mechanisms by… Expand Macroautophagy is a self-digesting pathway responsible for the removal of long-lived proteins and organelles by the lysosomal… Expand Autophagy induced by nutrient depletion is involved in survival during starvation conditions. In addition to starvation-induced… Expand The anti‐apoptotic proteins Bcl‐2 and Bcl‐XL bind and inhibit Beclin‐1, an essential mediator of autophagy. Here, we demonstrate… Expand Macroautophagy, a lysosomal pathway responsible for the turnover of organelles and long-lived proteins, has been regarded mainly… Expand During starvation-induced autophagy in mammals, autophagosomes form and fuse with lysosomes, leading to the degradation of the… Expand