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macroautophagy

Known as: autophagy in response to cellular starvation, non-specific autophagy, starvation-induced autophagy 
The major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of… 
National Institutes of Health

Related topics

Related topics

8 relations

Broader (2)

AutophagyProgrammed Cell Death, Type II

Narrower (2)

autophagosome maturationautophagosome organization
negative regulation of macroautophagynegative regulation of macroautophagy by TORC1 signalingpositive regulation of macroautophagyregulation of macroautophagy

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2019
Highly Cited
2019
MITF has a central role in regulating starvation-induced autophagy in melanoma
The MITF transcription factor is a master regulator of melanocyte development and a critical factor in melanomagenesis. The… 
Highly Cited
2015
Highly Cited
2015
Lipid droplets and their component triglycerides and steryl esters regulate autophagosome biogenesis
Autophagy is a major catabolic process responsible for the delivery of proteins and organelles to the lysosome/vacuole for… 
Highly Cited
2015
Highly Cited
2015
Transcriptional regulation of Annexin A2 promotes starvation-induced autophagy
Autophagy is an important degradation pathway, which is induced after starvation, where it buffers nutrient deprivation by… 
Highly Cited
2014
Highly Cited
2014
Functional role of autophagy-mediated proteome remodeling in cell survival signaling and innate immunity.
Highly Cited
2013
Highly Cited
2013
The TBC/RabGAP Armus Coordinates Rac1 and Rab7 Functions during Autophagy
Review
2012
Review
2012
Oxidative stress-induced autophagy in plants: the role of mitochondria.
Highly Cited
2011
Highly Cited
2011
Atg1‐mediated myosin II activation regulates autophagosome formation during starvation‐induced autophagy
Autophagy is a membrane‐mediated degradation process of macromolecule recycling. Although the formation of double‐membrane… 
Highly Cited
2009
Highly Cited
2009
Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3
The Hsc/Hsp70 co‐chaperones of the BAG (Bcl‐2‐associated athanogene) protein family are modulators of protein quality control. We… 
2006
2006
In yeast, loss of Hog1 leads to osmosensitivity of autophagy.
In mammalian liver, proteolysis is regulated by the cellular hydration state in a microtubule- and p38(MAPK) (p38 mitogen… 
Highly Cited
2005
Highly Cited
2005
Lysosomal Turnover, but Not a Cellular Level, of Endogenous LC3 is a Marker for Autophagy
During starvation-induced autophagy in mammals, autophagosomes form and fuse with lysosomes, leading to the degradation of the… 
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