autophagosome maturation

Known as: autophagic vacuole fusion, autophagic vacuole maturation, autophagosome fusion 
The process in which autophagosomes, double-membraned vacuoles containing cytoplasmic material fuse with a vacuole (yeast) or lysosome (e.g. mammals… (More)
National Institutes of Health

Papers overview

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2015
2015
mTORC1 plays a key role in autophagy as a negative regulator. The currently known targets of mTORC1 in the autophagy pathway… (More)
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2015
2015
Beclin 1, a protein essential for autophagy, regulates autophagy by interacting with Vps34 and other cofactors to form the Beclin… (More)
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Highly Cited
2012
Highly Cited
2012
Autophagy is a major catabolic pathway in eukaryotes associated with a broad spectrum of human diseases. In autophagy… (More)
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2011
2011
BACKGROUND Autophagy is essential to intracellular homeostasis and is involved in the pathophysiology of a variety of diseases… (More)
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Highly Cited
2009
Highly Cited
2009
Beclin 1, a mammalian autophagy protein that has been implicated in development, tumour suppression, neurodegeneration and cell… (More)
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2009
2009
Autophagy is a highly conserved cellular process responsible for the degradation of long-lived proteins and organelles. Autophagy… (More)
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Highly Cited
2009
Highly Cited
2009
Intracellular pathogens like Shigella flexneri enter host cells by phagocytosis. Once inside, the pathogen breaks the vacuolar… (More)
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Highly Cited
2008
Highly Cited
2008
Autophagic and endocytic pathways are tightly regulated membrane rearrangement processes that are crucial for homeostasis… (More)
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Highly Cited
2008
Highly Cited
2008
The two structurally related, major lysosomal membrane proteins LAMP-1 and LAMP-2 were for a long time regarded as crucial for… (More)
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Highly Cited
2007
Highly Cited
2007
The regulated clearance of mitochondria is a well recognized but poorly understood aspect of cellular homeostasis, and defects in… (More)
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