lomeguatrib

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2004-2018
012320042018

Papers overview

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2013
2013
Temozolomide (TMZ) is commonly used in the treatment of glioblastoma (GBM). The MGMT repair enzyme (O 6-methylguanine-DNA… (More)
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2011
2011
Background:The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) reverses the O6-methylguanine (O6-meG) lesion… (More)
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2010
2010
PURPOSE A major mechanism of resistance to chlorethylnitrosureas and methylating agents involves the DNA repair protein O(6… (More)
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2010
2010
Authors' A University Manches 3Neurosug NHS Trus Developme Urology, N 
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2009
2009
Lomeguatrib, an O6-methylguanine-DNA methyltransferase inactivator, was evaluated in an extended dosing regimen with temozolomide… (More)
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2009
2009
Expression of the DNA repair protein O 6-methylguanine-DNA methyltransferase (MGMT) correlates with resistance to irinotecan in… (More)
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2008
2008
To evaluate the tumour response to lomeguatrib and temozolomide (TMZ) administered for 5 consecutive days every 4 weeks in… (More)
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2007
2007
PURPOSE To evaluate tumor response, pharmacodynamic effects, and safety of a combination of lomeguatrib (LM), an O6-methylguanine… (More)
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2007
2007
Previous studies indicated that dacarbazine and Temozolomide could be highly effective against refractory acute leukaemia. Their… (More)
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2006
2006
PURPOSE A major mechanism of resistance to temozolomide involves the DNA repair protein O6-alkylguanine-DNA-alkyltransferase… (More)
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