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lobenzarit

Known as: lobenzart, 2-((2-carboxyphenyl)amino)-4-chlorobenzoic acid, Benzoic acid, 2-((2-carboxyphenyl)amino)-4-chloro-, disodium salt 
National Institutes of Health

Related topics

Related topics

5 relations

Broader (4)

Anti-Inflammatory Agents, Non-SteroidalImmunologic AdjuvantsImmunosuppressive Agentsortho-Aminobenzoates

Narrower (1)

lobenzarit disodium

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Repurposing the Chemical Scaffold of the Anti‐Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis
The emergence of extensively drug‐resistant strains of Mycobacterium tuberculosis (Mtb) highlights the need for new therapeutics… 
Highly Cited
2012
Highly Cited
2012
Identifying mechanism-of-action targets for drugs and probes
Notwithstanding their key roles in therapy and as biological probes, 7% of approved drugs are purported to have no known primary… 
2007
2007
Investigation of the influence of particle size on the excipient percolation thresholds of HPMC hydrophilic matrix tablets.
In previous papers of our research group, a linear relationship between the drug percolation threshold and the relative drug… 
1999
1999
Evaluation of Eudragit RS-PO and Ethocel 100 matrices for the controlled release of lobenzarit disodium.
Lobenzarit disodium is a drug for the treatment of rheumatoid arthritis. In this work, inert matrix tablets of lobenzarit… 
Highly Cited
1995
Highly Cited
1995
Effect of a novel anti-rheumatic drug, TA-383, on type II collagen-induced arthritis.
1995
1995
IL-6-mediated MHC class II induction on RIN-5AH insulinoma cells by IFN-γ occurs via the G-protein pathway
Major histocompatibility complex (MHC) class II antigen expression has been implicated in the pathogenesis of autoimmune type 1… 
1991
1991
Suppressive effect of anti-rheumatic drugs on interleukin-1 beta release from human peripheral blood monocytes.
1989
1989
Different inhibitory actions of immunomodulating agents and immunosuppressive agents on bone resorption of mouse calvaria.
1989
1989
Inhibition of Streptozocin-Induced Insulitis and Diabetes With Lobenzarit in CD-1 Mice
When multiple low doses (30 mg/kg body wt) of streptozocin were given to CD-1 mice, diabetes associated with L3T4 T-lymphocyte… 
1984
1984
A multicenter double-blind controlled study of lobenzarit, a novel immunomodulator, in rheumatoid arthritis.
A multicenter double-blind study was carried out in patients with rheumatoid arthritis (RA) by comparing treatment with a novel… 
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