Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

levoleucovorin

Known as: S leucovorin, levo leucovorin, (6S)-Folinic acid 
The active l-isomer of the racemic mixture of the 5-formyl derivative of tetrahydrofolic acid. Metabolically active, l-leucovorin, also known… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Summary Background Preoperative (neoadjuvant) chemotherapy and radiotherapy are more effective than similar postoperative… Expand
  • figure 1
  • table 1
  • figure 2
  • table 2
  • table 3
Is this relevant?
Highly Cited
2012
Highly Cited
2012
Background Preoperative (neoadjuvant) chemotherapy and radiotherapy are more effective than similar postoperative treatment for… Expand
Is this relevant?
Highly Cited
2011
Highly Cited
2011
Summary Background Elderly and frail patients with cancer, although often treated with chemotherapy, are under-represented in… Expand
  • figure 1
  • table 1
  • table 2
  • figure 2
  • table 3
Is this relevant?
Highly Cited
2008
Highly Cited
2008
PURPOSE Adjuvant systemic chemotherapy administered after surgical resection of colorectal cancer metastases may reduce the risk… Expand
Is this relevant?
Highly Cited
2007
Highly Cited
2007
BACKGROUND In the non-curative setting, the sequence in which anticancer agents are used, singly or in combination, may be… Expand
Is this relevant?
Highly Cited
2004
Highly Cited
2004
BACKGROUND The mechanism of action of 5-fluorouracil (5-FU) has been associated with inhibition of thymidylate synthase (TS) and… Expand
  • figure 1
  • figure 2
  • table 1
  • table 2
  • figure 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
PURPOSE This randomized, 2 x 2 factorial study compared a semimonthly (LVFU2) with a monthly (FULV) regimen of fluorouracil and… Expand
Is this relevant?
Highly Cited
2002
Highly Cited
2002
PURPOSE To evaluate the impact of tumor response; tumor and nodal downstaging; and cTNM, yTNM (clinical stage after… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
PURPOSE Response rates to fluorouracil (5-FU)-based therapy remain low. As new, active agents are being tested, information… Expand
Is this relevant?