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leukotriene-C4 synthase activity
Known as:
LTC4 synthetase activity
, (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming)
, leukotriene C4 synthetase activity
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Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). [EC:4.4.1.20, RHEA:17620]
National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Analysis of Human Multidrug Resistance Protein 1 (ABCC1) by Matrix-Assisted Laser Desorption Ionization/Time of Flight Mass Spectrometry: Toward Identification of Leukotriene C4 Binding Sites
Peng Wu
,
C. Oleschuk
,
Qingcheng Mao
,
B. Keller
,
R. Deeley
,
S. Cole
Molecular Pharmacology
2005
Corpus ID: 2250248
Multidrug resistance in tumor cells may be caused by reduced drug accumulation resulting from expression of one or more proteins…
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2002
2002
Uncoupled regulation of leukotriene C4 synthase in platelets from aspirin‐intolerant asthmatics and healthy volunteers after aspirin treatment
S. Tornhamre
,
A. Ehnhage
,
K. Kölbeck
,
C. Edenius
,
J. Lindgren
Clinical and Experimental Allergy
2002
Corpus ID: 38326047
Background We have reported that thromboxane A2 induces suppression of leukotriene (LT) C4 synthase activity in human platelets.
1997
1997
Post-transcriptional regulation of LTC4 synthase activity by retinoic acid in rat basophilic leukemia cells.
Y. Hamasaki
,
M. Murakami
,
I. Kudo
,
S. Miyazaki
Biochimica et Biophysica Acta
1997
Corpus ID: 31655023
1994
1994
Abnormal leukotriene C4 released by unaffected jejunal mucosa in patients with inactive Crohn's disease.
F. Casellas
,
F. Guarner
,
M. Antolín
,
R. Rodriguez
,
A. Salas
,
J. Malagelada
Gut
1994
Corpus ID: 9364766
The mucosal release of inflammatory mediators is enhanced in active inflammatory bowel disease. This study examines whether…
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Review
1989
Review
1989
[Cardiovascular effects of leukotrienes].
J. Fauler
,
J. Frölich
Zeitschrift für Kardiologie
1989
Corpus ID: 25512447
Leukotrienes are among the most potent lipid mediators of inflammation. Leukotriene B4 is one of the most potent endogenously…
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1988
1988
Effect of azelastine on bronchoconstriction induced by histamine and leukotriene C4 in patients with extrinsic asthma.
M. Albazzaz
,
K R Patel
Thorax
1988
Corpus ID: 1700932
Azelastine, a new oral agent with antiallergic and antihistamine properties, has been shown to inhibit the effect of histamine…
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Highly Cited
1987
Highly Cited
1987
Purification of a new acidic glutathione S-transferase, GST-Yn1Yn1, with a high leukotriene-C4 synthase activity from rat brain.
S. Tsuchida
,
T. Izumi
,
+4 authors
K. Sato
European Journal of Biochemistry
1987
Corpus ID: 40840322
A new acidic form of glutathione S-transferase (GST, pI 6.2) was purified from rat brain by S-hexylglutathione affinity…
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1986
1986
LTC4 ‘receptor’: its demonstration using airway and non-airway tissues
John B. Cheng
1986
Corpus ID: 73064099
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