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leukotriene-C4 synthase activity

Known as: LTC4 synthetase activity, (7E,9E,11Z,14Z)-(5S,6R)-6-(glutathion-S-yl)-5-hydroxyicosa-7,9,11,14-tetraenoate glutathione-lyase (epoxide-forming), leukotriene C4 synthetase activity 
Catalysis of the reaction: leukotriene C(4) = glutathione + leukotriene A(4). [EC:4.4.1.20, RHEA:17620]
National Institutes of Health

Papers overview

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2002
2002
Background We have reported that thromboxane A2 induces suppression of leukotriene (LT) C4 synthase activity in human platelets. 
1994
1994
The mucosal release of inflammatory mediators is enhanced in active inflammatory bowel disease. This study examines whether… 
Review
1989
Review
1989
Leukotrienes are among the most potent lipid mediators of inflammation. Leukotriene B4 is one of the most potent endogenously… 
1988
1988
Azelastine, a new oral agent with antiallergic and antihistamine properties, has been shown to inhibit the effect of histamine… 
Highly Cited
1987
Highly Cited
1987
A new acidic form of glutathione S-transferase (GST, pI 6.2) was purified from rat brain by S-hexylglutathione affinity…