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lesinurad

Known as: {[5-bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}acetic acid 
 
National Institutes of Health

Papers overview

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Highly Cited
2017
Highly Cited
2017
Objectives Determine the efficacy and safety of daily lesinurad (200 or 400 mg orally) added to allopurinol in patients with… Expand
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Highly Cited
2017
Highly Cited
2017
OBJECTIVE Lesinurad is a selective uric acid reabsorption inhibitor used for the treatment of gout in combination with a xanthine… Expand
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Highly Cited
2017
Highly Cited
2017
Objective To investigate the efficacy and safety of lesinurad in combination with febuxostat in a 12‐month phase III trial in… Expand
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2017
2017
Objective To investigate the efficacy and safety of lesinurad, a selective uric acid reabsorption inhibitor, in a 6 month, phase… Expand
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Highly Cited
2016
Highly Cited
2016
Objectives To assess the efficacy and tolerability of lesinurad, an oral selective uric acid reabsorption inhibitor, in… Expand
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2016
2016
In silico absorption modeling has been performed, to assess the impact of in vitro dissolution on in vivo performance for… Expand
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Review
2016
Review
2016
Lesinurad (ZURAMPIC®) is an oral urate–anion exchanger transporter 1 (URAT1) inhibitor developed by Ardea Biosciences (a… Expand
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2016
2016
Background and ObjectivesLesinurad is a selective uric acid reabsorption inhibitor (SURI) under investigation for the treatment… Expand
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2015
2015
Lesinurad is a selective uric acid reabsorption inhibitor under investigation for the treatment of gout. Single and multiple… Expand
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Highly Cited
2014
Highly Cited
2014
OBJECTIVE The aim of this study was to evaluate the pharmacodynamics (PDs), pharmacokinetics (PKs) and safety of lesinurad… Expand
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