Skip to search formSkip to main contentSkip to account menu
  • Publications
  • Influence
2012 American College of Rheumatology guidelines for management of gout. Part 1: Systematic nonpharmacologic and pharmacologic therapeutic approaches to hyperuricemia
DINESH KHANNA, JOHN D. FITZGERALD, PUJA P. KHANNA, SANGMEE BAE, MANJIT K. SINGH, TUHINA NEOGI, MICHAEL H. PILLINGER, JOAN MERILL, SUSAN LEE, SHRADDHA PRAKASH, MARIAN KALDAS, MANEESH GOGIA, FERNANDO…
View on Wiley
2012 American College of Rheumatology guidelines for management of gout. Part 2: Therapy and antiinflammatory prophylaxis of acute gouty arthritis
TLDR
These guidelines for the management and anti-inflammatory prophylaxis of acute attacks of gouty arthritis complements the manuscript on guidelines to treat hyperuricemia in patients with evidence of gouts and involves a diverse and international panel of experts.
View on Wiley
Mechanisms of inflammation in gout.
TLDR
This review article outlines recent advances in the understanding of the mechanisms of inflammation in gout and proposes a unifying model of gout involving the differential role of mononuclear phagocytes in the regulation of the inflammatory response to MSU crystals.
View on PubMed
2015 Gout classification criteria: an American College of Rheumatology/European League Against Rheumatism collaborative initiative
TLDR
The new classification criteria, developed using a data-driven and decision-analytic approach, have excellent performance characteristics and incorporate current state-of-the-art evidence regarding gout.
View on BMJ
National prevalence of gout derived from administrative health data in Aotearoa New Zealand.
TLDR
Applying algorithms to national administrative data sets provides a readily available method for estimating the prevalence of a chronic condition such as gout, where diagnosis and drug treatment are relatively specific for this disease.
View on PubMed
Starting dose is a risk factor for allopurinol hypersensitivity syndrome: a proposed safe starting dose of allopurinol.
TLDR
It is indicated that starting allopurinol at a dose of 1.5 mg per unit of estimated GFR may be associated with a reduced risk of AHS, and the dose can be gradually increased to achieve the target serum urate level.
View on PubMed
A subset of natural killer cells is greatly expanded within inflamed joints.
TLDR
The study showed that the CD3-, CD56(bright) subset of NK cells was greatly expanded within inflamed joints and rendered them good candidates for a role in interacting with the macrophage/monocyte population within the joint, thus amplifying the production of proinflammatory cytokines.
View on PubMed
2015 Gout Classification Criteria: An American College of Rheumatology/European League Against Rheumatism Collaborative Initiative
Existing criteria for the classification of gout have suboptimal sensitivity and/or specificity, and were developed at a time when advanced imaging was not available. The current effort was…
View on Wiley
A Review of Uric Acid, Crystal Deposition Disease, and Gout
TLDR
Evidence suggest that an early approach to the treatment of gout and associated comorbidities is advisable, that new imaging techniques may help to evaluate both the burden of deposition and response to urate-lowering treatment in selected patients, and that the final strategic objective of healthcare for patients with gout is to completely resolve urate crystal deposits.
View on Springer
A strong role for the ABCG2 gene in susceptibility to gout in New Zealand Pacific Island and Caucasian, but not Māori, case and control sample sets.
TLDR
The results emphasize the need to account for sub-population differences when undertaking biomedical genetic research in a group defined by a geographical region and shared ancestry but characterized by migratory events that create bottlenecks and altered genetic structure in the founder populations.
View on PubMed
...
...
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License