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leptin

Known as: Obese Gene Product, Obesity Factor, Obese Protein 
A 16-kDa peptide hormone secreted from WHITE ADIPOCYTES. Leptin serves as a feedback signal from fat cells to the CENTRAL NERVOUS SYSTEM in… 
National Institutes of Health

Related topics

Related topics

29 relations
Adipocytokine Signaling PathwayBioenergeticsDesire for foodDiabetes Mellitus

Broader (2)

Adipose tissuepeptide hormone

Narrower (5)

LY396623leptin (116-130)metreleptinmurine leptin analog

Papers overview

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Highly Cited
2016
Highly Cited
2016
Reversing the Effects of Maternal Obesity
Obese women tend to give birth to overweight offspring who have a predisposition to metabolic disease and obesity. This effect… 
2014
2014
Urinary proteomics in obstructive sleep apnoea and obesity
Obstructive sleep apnoea (OSA) is a common complication of obesity and can have a substantial negative impact on a patient's… 
2010
2010
Letter by Minciu Macrea et al regarding article, "Leptin signaling in the failing and mechanically unloaded human heart".
To the Editor: In their article “Leptin signaling in the failing and mechanically unloaded human heart,” McGaffin et al1… 
Highly Cited
2008
Highly Cited
2008
Gastroprotective effect of leptin in indomethacin-induced gastric injury.
This study investigated the involvement of neutrophil infiltration, disturbances in nitric oxide (NO) generation and oxidative… 
Highly Cited
2008
Highly Cited
2008
Neural Integration of Peripheral Signals Implicated in the Control of Energy Homeostasis and Metabolism Mechanisms mediating renal sympathetic activation to leptin in obesity
Morgan DA, Thedens DR, Weiss R, Rahmouni K. Mechanisms mediating renal sympathetic activation to leptin in obesity. Am J Physiol… 
2007
2007
Fetal Programming of Type 2 Diabetes
Hales and Barker (1) caused a paradigm shift in our thinking about diabetes prevention when they demonstrated that low birth… 
2004
2004
Effects of chronic nitric oxide inhibition on the renal excretory response to leptin.
OBJECTIVE Previous investigations have demonstrated that leptin promotes natriuresis with a renal tubular effect. However, the… 
1998
1998
The effects of glucocorticoids on leptin levels in humans may be restricted to acute pharmacologic dosing.
unteers to pharmacologic doses of dexamethasone. These studies used high total doses of dexamethasone (1–15 mg) over periods of 1… 
1984
1984
Adipose tissue characteristics of ex-obese long-distance runners.
Mean fat cell diameter and lipolytic activities of adipose tissue were determined in five ex-obese runners (EOR) who had… 
1983
1983
A behavioral assessment of arcuate nucleus damage after a single injection of monosodium glutamate.
The behavioral and histological consequences of the administration of a single injection of monosodium glutamate (MSG) to… 
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