Bioenergetics

Harnessing energy as ion gradients across membranes is as universal as the genetic code. We leverage new insights into anaerobe… (More)

Mechanisms that regulate cellular metabolism are a fundamental requirement of all cells. Most eukaryotic cells rely on aerobic… (More)

Mitochondrial dysfunction has been proposed to play a pivotal role in neurodegenerative diseases, including Alzheimer's disease… (More)

In contrast to normal differentiated cells, which rely primarily on mitochondrial oxidative phosphorylation to generate the… (More)

Mitochondrial bioenergetics plays a key role in multiple basic cellular processes, such as energy production, nucleotide… (More)

Increased conversion of glucose to lactic acid associated with decreased mitochondrial respiration is a unique feature of tumors… (More)

Mitochondria form a dynamic network, and it remains unclear how the alternate configurations interact with bioenergetics… (More)

Irrespective of the morphological features of end-stage cell death (that may be apoptotic, necrotic, autophagic, or mitotic… (More)

Age-related accumulation of cellular damage and death has been linked to oxidative stress. Calorie restriction (CR) is the most… (More)

Examination of microbial diversity in environments of increasing salt concentrations indicates that certain types of… (More)