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leptin receptor

Known as: Receptor, OB, HuB219, OB Receptor 
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is… 
National Institutes of Health

Related topics

Related topics

39 relations
Adipocytokine Signaling PathwayCytokine Receptor GeneCytokine Signaling ProcessCytoplasmic Domain

Narrower (4)

OBRa ReceptorOBRb Receptorleptin receptor, humanleptin receptor, mouse

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Molecular dynamics, dynamic site mapping, and highthroughput virtual screening on leptin and the Ob receptor as anti-obesity target
AbstractBody weight control is a mechanism finely regulated by several hormonal, metabolic, and nervous pathways. The leptin… 
Highly Cited
2006
Highly Cited
2006
Neonatal leptin treatment programmes leptin hypothalamic resistance and intermediary metabolic parameters in adult rats.
We previously showed that neonatal leptin treatment programmes higher body weight and food intake in adult rats. Here we… 
Highly Cited
2002
Highly Cited
2002
Selective Resistance to Central Neural Administration of Leptin in Agouti Obese Mice
Abstract—We recently demonstrated that in a rodent model of obesity (agouti yellow mice), there is a selective leptin resistance… 
Highly Cited
2002
Highly Cited
2002
Leptin enhances the effect of transforming growth factor beta in increasing type I collagen formation.
Highly Cited
1999
Highly Cited
1999
Activation of SOCS-3 Messenger Ribonucleic Acid in the Hypothalamus by Ciliary Neurotrophic Factor.
Ciliary neurotrophic factor (CNTF) is a neurocytokine expressed in glial cells that acts on brain cells to promote gene… 
Highly Cited
1997
Highly Cited
1997
Cloning and characterization of a human leptin receptor using a biologically active leptin immunoadhesin.
Leptin, the product of the ob gene, is a hormone secreted by fat cells which is primarily involved in the regulation of body… 
Review
1997
Review
1997
Regulation of ob gene and overexpression in obesity.
  • M. Guerre-Millo
  • Biomedicine & pharmacotherapy = Biomedecine…
  • 1997
  • Corpus ID: 2855502
Highly Cited
1997
Highly Cited
1997
Leptin receptors in the adrenal medulla of the rat.
Leptin is the protein product of the recently cloned obesity gene. Leptin receptor mRNA is found in a number of central and… 
Highly Cited
1996
Highly Cited
1996
Autoradiographic localization of leptin binding in the choroid plexus of ob/ob and db/db mice.
The obese gene product, leptin, is synthesized in adipose tissue and is a circulating factor regulating body weight. To identify… 
Highly Cited
1996
Highly Cited
1996
Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human.
As part of an effort to identify informative molecular markers for genetic analysis of human pedigrees segregating for obesity… 
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