leptin receptor

Known as: Receptor, OB, HuB219, OB Receptor 
Cell surface receptors for obesity factor (LEPTIN), a hormone secreted by the WHITE ADIPOCYTES. Upon leptin-receptor interaction, the signal is… (More)
National Institutes of Health

Papers overview

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Review
2008
Review
2008
The adipose tissue-derived hormone leptin acts via its receptor (LRb) in the brain to regulate energy balance and neuroendocrine… (More)
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Highly Cited
2006
Highly Cited
2006
The leptin hormone is critical for normal food intake and metabolism. While leptin receptor (Lepr) function has been well studied… (More)
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Highly Cited
2004
Highly Cited
2004
Neuroanatomical and electrophysiological studies have shown that hypothalamic POMC neurons are targets of the adipostatic hormone… (More)
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Highly Cited
2003
Highly Cited
2003
Secretion of leptin from adipocytes communicates body energy status to the brain by activating the leptin receptor long form (LRb… (More)
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Highly Cited
2001
Highly Cited
2001
Leptin is the primary signal through which the hypothalamus senses nutritional state and modulates food intake and energy balance… (More)
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Highly Cited
1998
Highly Cited
1998
Obesity is associated with an increased incidence of infection, diabetes, and cardiovascular disease, which together account for… (More)
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Highly Cited
1996
Highly Cited
1996
MUTATIONS in the mouse diabetes(db) gene result in obesity and diabetes in a syndrome resembling morbid human obesity1. Previous… (More)
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Highly Cited
1996
Highly Cited
1996
OB-R is a high affinity receptor for leptin, an important circulating signal for the regulation of body weight. We identified an… (More)
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Highly Cited
1996
Highly Cited
1996
The hypothesis that leptin (OB protein) acts in the hypothalamus to reduce food intake and body weight is based primarily on… (More)
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Highly Cited
1996
Highly Cited
1996
A TOTAL deficiency in or resistance to the protein leptin causes severe obesity1–4. As leptin levels rise with increasing… (More)
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