lens fiber cell differentiation

Known as: lens fibre cell differentiation 
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells… (More)
National Institutes of Health

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Broader (1)

lens development in camera-type eye

Narrower (1)

lens fiber cell development
negative regulation of lens fiber cell differentiationpositive regulation of lens fiber cell differentiation

Papers overview

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2009
2009
Calpain expression and activity during lens fiber cell differentiation.
In animal models, the dysregulated activity of calcium-activated proteases, calpains, contributes directly to cataract formation… (More)
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Highly Cited
2008
Highly Cited
2008
Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation.
The vertebrate lens provides an excellent model to study the mechanisms that regulate terminal differentiation. Although… (More)
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2007
2007
Structural specializations emerging late in mouse lens fiber cell differentiation.
PURPOSE To describe a previously uncharacterized structural specialization in the mouse lens fiber cell and to delineate its… (More)
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2004
2004
Wnt signaling enhances FGF2-triggered lens fiber cell differentiation.
Wnt signaling is implicated in many developmental processes, including cell fate changes. Several members of the Wnt family, as… (More)
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Highly Cited
2002
Highly Cited
2002
Bone morphogenetic protein signaling and the initiation of lens fiber cell differentiation.
Previous studies showed that the retina produces factors that promote the differentiation of lens fiber cells, and identified… (More)
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2000
2000
Stabilization and remodeling of the membrane skeleton during lens fiber cell differentiation and maturation.
Actin filaments are integral components of the plasma membrane-associated cytoskeleton (membrane skeleton) and are believed to… (More)
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1995
1995
Filensin is proteolytically processed during lens fiber cell differentiation by multiple independent pathways.
Filensin is a lens-specific intermediate filament protein, expressed in the lens fiber cells but not the lens epithelium. Using… (More)
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Highly Cited
1994
Highly Cited
1994
Altered cell cycle regulation in the lens of HPV-16 E6 or E7 transgenic mice: implications for tumor suppressor gene function in development.
Tumor suppressor proteins are believed to play a role in regulating cell cycle control during mammalian development. The E6 and… (More)
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Highly Cited
1992
Highly Cited
1992
Coincident loss of mitochondria and nuclei during lens fiber cell differentiation.
During normal differentiation, lens fiber cells lose their nuclei, mitochondria, and other membrane-bound organelles. In the… (More)
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1984
1984
A cytoskeletal protein unique to lens fiber cell differentiation.
A chick lens urea-soluble polypeptide of estimated mol. wt. 49 000 daltons is unique to fiber cell differentiation and is a… (More)
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