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lens epithelial cell proliferation

The multiplication or reproduction of lens epithelial cells, resulting in the expansion of a cell population. Lens epithelial cells make up the lens… 
National Institutes of Health

Related topics

Related topics

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Broader (1)

lens development in camera-type eye

Papers overview

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2010
2010
Visualizing lens epithelial cell proliferation in whole lenses
Purpose To develop a means to image cells in S-phase of the cell cycle while preserving the anatomic relationships within the… 
Highly Cited
2006
Highly Cited
2006
Suppression of human lens epithelial cell proliferation by proteasome inhibition, a potential defense against posterior capsular opacification.
PURPOSE Posterior capsular opacification (PCO) is caused by the proliferation, migration, and epithelial-mesenchymal transition… 
Highly Cited
2005
Highly Cited
2005
Deregulation of Lens Epithelial Cell Proliferation and Differentiation during the Development of TGFβ-Induced Anterior Subcapsular Cataract
Normal lens development and growth is dependent on the tight spatial and temporal regulation of lens cell proliferation and fiber… 
2004
2004
Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.
PURPOSE To investigate the ability of insulin-like growth factor (IGF)-1 to prevent apoptosis in lens epithelial cells and the… 
Highly Cited
2003
Highly Cited
2003
Growth factor induced activation of Rho and Rac GTPases and actin cytoskeletal reorganization in human lens epithelial cells.
PURPOSE To determine the involvement of the Rho GTPases-mediated signaling pathway in growth factor-stimulated actomyosin… 
Highly Cited
2002
Highly Cited
2002
Transition between proliferation and differentiation for lens epithelial cells is regulated by Src family kinases
As in many cell types, lens cells must withdraw from the cell cycle before they initiate their differentiation. The involvement… 
2000
2000
Inhibition of rabbit keratocyte and human fetal lens epithelial cell proliferation by retrovirus-mediated transfer of antisense cyclin G1 and antisense MAT1 constructs.
The aim of this study is to evaluate the potential of gene transfer of cell cycle control genes as treatment of corneal haze or… 
Highly Cited
1997
Highly Cited
1997
Human lens epithelial cell proliferation in a protein-free medium.
PURPOSE The ocular humors are relatively low in protein, yet cell growth in the human capsular bag still occurs after… 
1994
1994
Modulation of lens epithelial cell proliferation by enhanced prostaglandin synthesis after UVB exposure.
PURPOSE The goals of this investigation were to examine the synthesis of prostaglandins after UVB exposure of lens epithelial… 
Highly Cited
1988
Highly Cited
1988
In vitro inhibition of lens epithelial cell proliferation and migration.
Delayed opacification of the posterior capsule is the most common cause of decreased visual acuity after extracapsular cataract… 
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