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lebrikizumab

Known as: Immunoglobulin G4, Anti-(Human Interleukin 13) (Human-Mouse Monoclonal MILR1444a Gamma-4-Chain), Disulfide with Human-Mouse Monoclonal MILR1444a Kappa-Chain, Dimer, MILR1444A, PRO301444 
A humanized monoclonal antibody against interleukin 13 (IL-13) with immunosuppressive and anti-asthmatic activities. Lebrikizumab binds to IL-13 and… 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Monoclonal Antibodies
antigen binding

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Therapeutic Potential of Lebrikizumab in the Treatment of Atopic Dermatitis
Background Atopic dermatitis (AD) is a chronic, relapsing skin condition with a wide disease spectrum. Moderate-to-severe cases… 
Review
2016
Review
2016
Molecular Mechanisms of Cutaneous Inflammatory Disorder: Atopic Dermatitis
Atopic dermatitis (AD) is a multifactorial inflammatory skin disease resulting from interactions between genetic susceptibility… 
Review
2016
Review
2016
Personalized Medicine in Allergy
Allergic disease is among the most common pathologies worldwide and its prevalence has constantly increased up to the present… 
Review
2016
Review
2016
Roles of Periostin in Respiratory Disorders.
Periostin is a matricellular protein that has been implicated in many disease states. It interacts with multiple signaling… 
Review
2016
Review
2016
A Critical Evaluation of Anti-IL-13 and Anti-IL-4 Strategies in Severe Asthma
Asthma is a high-prevalence disease, still accounting for mortality and high direct and indirect costs. It is now recognized that… 
Review
2015
Review
2015
The past, present, and future of monoclonal antibodies to IL-5 and eosinophilic asthma: a review
Asthma is a heterogeneous syndrome that might be better described as a constellation of phenotypes or endotypes, each with… 
Highly Cited
2013
Highly Cited
2013
The effects of lebrikizumab in patients with mild asthma following whole lung allergen challenge
Interleukin 13 (IL13) is a T‐helper type 2 (Th2) cytokine associated with inflammation and pathology in allergic diseases such as… 
Highly Cited
2013
Highly Cited
2013
Structural basis of signaling blockade by anti-IL-13 antibody Lebrikizumab.
2013
2013
Releasing the brake on puberty.
What is so magical about the age at onset of puberty in humans — currently set at approximately 11 years of age?1 Why not 6 or 16… 
Review
2013
Review
2013
Which are the antibodies to watch in 2013?
The start of the new year signals that it is time for mAbs’ annual review of the therapeutic monoclonal antibodies (mAbs) in… 
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