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latrepirdine

Known as: 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)-ethyl)-1H-pyrid(4,3b)indole, dimebone, Dimebon 
National Institutes of Health

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Review
2017
Review
2017
New symptomatic therapies for Huntington disease.
2013
2013
The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti‐Alzheimer Multitarget Profile of Dimebon
Alzheimer’s disease (AD) is an extremely challenging and often frustrating area of drug discovery. Since the withdrawal of… 
2012
2012
Dimebon Reduces the Levels of Aggregated Amyloidogenic Protein Forms in Detergent-Insoluble Fractions In Vivo
Aggregation of proteins liable to assembling into fi brils with subsequent formation of amyloid incorporations is an important… 
Highly Cited
2011
Highly Cited
2011
Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; synthesis of dimebolin.
A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl… 
2010
2010
Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles.
Review
2010
Review
2010
[Development of new drugs for Alzheimer's disease].
Currently, only donepezil is available for the treatment of Alzheimer disease (AD) in Japan. Clinical trials of galantamine… 
Review
2009
Review
2009
Amyloid beta: a putative intra-spinal microtubule-depolymerizer to induce synapse-loss or dentritic spine shortening in Alzheimer's disease.
A loss or shortening of dendritic spines has been described in patients with neurodegenerative disorders such as Alzheimer's… 
Review
2009
Review
2009
Dimebon as a Potential Therapy for Alzheimer's Disease
Excellent treatment for Alzheimer's disease remains an unmet medical need. Although current therapies improve patients' abilities… 
2008
2008
Dimebon in Alzheimer's disease: old drug for new indication
1986
1986
Neurotransmitter mechanisms of the action of the antihistamine dimebon on the brain
To discover the possible mechanism of the stimulating effect of dimebon on the CNS, the action of the drug was studied on… 
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