latrepirdine

Known as: 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)-ethyl)-1H-pyrid(4,3b)indole, dimebone, Dimebon 
 
National Institutes of Health

Papers overview

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Review
2015
Review
2015
BACKGROUND Current treatments for Alzheimer's disease (AD) provide modest symptomatic relief but do not slow the progression of… (More)
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2013
2013
Latrepirdine (Dimebon) is a pro-neurogenic, antihistaminic compound that has yielded mixed results in clinical trials of mild to… (More)
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2013
2013
Latrepirdine (Dimebon; dimebolin) is a neuroactive compound that was associated with enhanced cognition, neuroprotection and… (More)
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2012
2012
Latrepirdine (Dimebon), an anti-histamine, has shown some benefits in trials of neurodegenerative diseases characterized by… (More)
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2012
2012
The prevalence of depression increases with aging. We hypothesized that like humans, old animals exhibit anhedonic-like behavior… (More)
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2010
2010
OBJECTIVES To evaluate the safety and tolerability of latrepirdine in Huntington disease (HD) and explore its effects on… (More)
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Review
2010
Review
2010
Transactivation response (TAR) DNA-binding protein of Mr 43 kDa (TDP-43) is a major component of the tau-negative and ubiquitin… (More)
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2009
2009
Dimebolin (Dimebon), is a non-selective antihistamine approved in Russia for the treatment of allergy. Recently, this drug has… (More)
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2008
2008
In drug development, sometimes you find what you’re not looking for. In July, at the annual meeting of the Alzheimer’s… (More)
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Highly Cited
2008
Highly Cited
2008
BACKGROUND Although treatments for Alzheimer's disease sometimes improve cognition, functional ability, or behaviour compared… (More)
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