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latrepirdine
Known as:
2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)-ethyl)-1H-pyrid(4,3b)indole
, dimebone
, Dimebon
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National Institutes of Health
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2017
Review
2017
New symptomatic therapies for Huntington disease.
A. Deb
,
S. Frank
,
C. Testa
Handbook of Clinical Neurology
2017
Corpus ID: 4233836
2013
2013
The Bivalent Ligand Approach as a Tool for Improving the in vitro Anti‐Alzheimer Multitarget Profile of Dimebon
M. Rosini
,
E. Simoni
,
+9 authors
M. Bolognesi
ChemMedChem
2013
Corpus ID: 205647462
Alzheimer’s disease (AD) is an extremely challenging and often frustrating area of drug discovery. Since the withdrawal of…
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2012
2012
Dimebon Reduces the Levels of Aggregated Amyloidogenic Protein Forms in Detergent-Insoluble Fractions In Vivo
A. Ustyugov
,
T. Shelkovnikova
,
+5 authors
N. Ninkina
Bulletin of experimental biology and medicine
2012
Corpus ID: 9343489
Aggregation of proteins liable to assembling into fi brils with subsequent formation of amyloid incorporations is an important…
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Highly Cited
2011
Highly Cited
2011
Ruthenium-catalyzed γ-carbolinium ion formation from aryl azides; synthesis of dimebolin.
Huijun Dong
,
R. T. Latka
,
T. Driver
Organic Letters
2011
Corpus ID: 20007712
A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl…
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2010
2010
Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles.
A. Ivachtchenko
,
E. Frolov
,
O. Mitkin
,
S. Tkachenko
,
I. Okun
,
A. V. Khvat
Bioorganic & Medicinal Chemistry Letters
2010
Corpus ID: 37728778
Review
2010
Review
2010
[Development of new drugs for Alzheimer's disease].
T. Tabira
Brain and nerve = Shinkei kenkyu no shinpo
2010
Corpus ID: 44841768
Currently, only donepezil is available for the treatment of Alzheimer disease (AD) in Japan. Clinical trials of galantamine…
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Review
2009
Review
2009
Amyloid beta: a putative intra-spinal microtubule-depolymerizer to induce synapse-loss or dentritic spine shortening in Alzheimer's disease.
F. Mitsuyama
,
Y. Futatsugi
,
+6 authors
Tadashi Koide
Italian journal of anatomy and embryology…
2009
Corpus ID: 20298048
A loss or shortening of dendritic spines has been described in patients with neurodegenerative disorders such as Alzheimer's…
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Review
2009
Review
2009
Dimebon as a Potential Therapy for Alzheimer's Disease
R. Doody
CNS Spectrums
2009
Corpus ID: 36819471
Excellent treatment for Alzheimer's disease remains an unmet medical need. Although current therapies improve patients' abilities…
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2008
2008
Dimebon in Alzheimer's disease: old drug for new indication
A. Burns
,
R. Jacoby
The Lancet
2008
Corpus ID: 9890258
1986
1986
Neurotransmitter mechanisms of the action of the antihistamine dimebon on the brain
S. K. Shadurskaya
,
A. Khomenko
,
V. A. Pereverzev
,
A. I. Balakeevskii
Bulletin of experimental biology and medicine
1986
Corpus ID: 35937921
To discover the possible mechanism of the stimulating effect of dimebon on the CNS, the action of the drug was studied on…
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