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latrepirdine

Known as: 2,3,4,5-tetrahydro-2,8-dimethyl-5-(2-(6-methyl-3-pyridyl)-ethyl)-1H-pyrid(4,3b)indole, dimebone, Dimebon 
National Institutes of Health

Papers overview

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2013
2013
Alzheimer’s disease (AD) is an extremely challenging and often frustrating area of drug discovery. Since the withdrawal of… 
2012
2012
Aggregation of proteins liable to assembling into fi brils with subsequent formation of amyloid incorporations is an important… 
Highly Cited
2011
Highly Cited
2011
A range of γ-carbolines were produced stereoselectively from ruthenium(III)-catalyzed reactions of 3-pyridyl substituted aryl… 
Review
2010
Review
2010
Currently, only donepezil is available for the treatment of Alzheimer disease (AD) in Japan. Clinical trials of galantamine… 
Review
2009
Review
2009
A loss or shortening of dendritic spines has been described in patients with neurodegenerative disorders such as Alzheimer's… 
Review
2009
Review
2009
Excellent treatment for Alzheimer's disease remains an unmet medical need. Although current therapies improve patients' abilities… 
1986
1986
To discover the possible mechanism of the stimulating effect of dimebon on the CNS, the action of the drug was studied on…