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Dementia prevention, intervention, and care
TLDR
The Lancet Commission on Dementia Prevention, Intervention, and Care met to consolidate the huge strides that have been made and the emerging knowledge as to what the authors should do to prevent and manage dementia. Expand
Clinical diagnosis of Alzheimer's disease
There are a number of ways in which a clinical diagnosis of dementia of the Alzheimer type can be made – the application of clinical criteria is the commonest but ancillary techniques such as neuroima
Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
Author(s): Livingston, Gill; Huntley, Jonathan; Sommerlad, Andrew; Ames, David; Ballard, Clive; Banerjee, Sube; Brayne, Carol; Burns, Alistair; Cohen-Mansfield, Jiska; Cooper, Claudia; Costafreda,Expand
Observations on the brains of demented old people. B.E. Tomlinson, G. Blessed and M. Roth, Journal of the Neurological Sciences (1970) 11, 205–242; (1968) 7, 331–356
This is a series in which key papers in old age psychiatry are presented with an introduction, commentary by the original author and current update by someone working in the field. A fullExpand
The Effects of Donepezil in Alzheimer’s Disease – Results from a Multinational Trial1
TLDR
The results of this study confirm that donepezil is effective and well tolerated in treating the symptoms of mild to moderately severe AD. Expand
Donepezil and memantine for moderate-to-severe Alzheimer's disease.
TLDR
In patients with moderate or severe Alzheimer's disease, continued treatment with donepezil was associated with cognitive benefits that exceeded the minimum clinically important difference and with significant functional benefits over the course of 12 months. Expand
Determinants of carer stress in Alzheimer's disease
TLDR
The impact of subgroups and individual symptoms of non‐cognitive disturbance on the carers of Alzheimer's disease patients are explored. Expand
Sertraline or mirtazapine for depression in dementia (HTA-SADD): a randomised, multicentre, double-blind, placebo-controlled trial
TLDR
Because of the absence of benefit compared with placebo and increased risk of adverse events, the present practice of use of these antidepressants, with usual care, for first-line treatment of depression in Alzheimer's disease should be reconsidered. Expand
A New Version of the Geriatric Depression Scale for Nursing and Residential Home Populations: The Geriatric Depression Scale (Residential) (GDS-12R)
The objective was to develop a new short-form Geriatric Depression Scale (GDS-12R) suitable for older people living in nursing and residential care settings, including those persons with significantExpand
'Justifiable depression': how primary care professionals and patients view late-life depression? A qualitative study.
TLDR
A need for the development of evidence-based provision for older people with depression within primary care, but also a need for elderly patients to be made aware of the legitimacy of presenting low mood and misery to their primary care professional. Expand
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