lasonolide A
National Institutes of Health
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Genetic screens in cultured human cells represent a powerful unbiased strategy to identify cellular pathways that determine drug…
Lasonolide A (LSA), a potent antitumor polyketide from the marine sponge, Forcepia sp., induces rapid and reversible protein…
Lasonolide A is a novel polyketide displaying potent anticancer activity across a broad range of cancer cell lines. Here, an…
Total synthetic studies on natural products with promising biological profiles, coupled with their intriguing structural features…
Lasonolide A (LSA) is a natural product with high and selective cytotoxicity against mesenchymal cancer cells, including leukemia…
Lasonolide A, a novel polyketide-derived macrolide, was previously identified from an extract of the marine sponge Forcepia sp…
The proposed structure of lasonolide A was synthesized employing radical cyclization reactions of beta-alkoxyacrylates for…
Total synthesis of the unnatural (-)-enantiomer of lasonolide A was achieved starting from ethyl l-malate. The two…