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lapachol

Known as: 2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphtho-quinone 
National Institutes of Health

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9 relations

Broader (7)

AnthelminticsAnti-Infective AgentsAntifungal AgentsAntimalarials

Narrower (2)

NSC-11905lapachol, sodium salt

Papers overview

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2014
2014
Beyond Topoisomerase Inhibition: Antitumor 1,4‐Naphthoquinones as Potential Inhibitors of Human Monoamine Oxidase
Monoamine oxidase (MAO) action has been involved in the regulation of neurotransmitters levels, cell signaling, cellular growth… 
2011
2011
Lapachol as an epithelial tumor inhibitor agent in Drosophila melanogaster heterozygote for tumor suppressor gene wts.
The search for new and effective antitumor agents with fewer cytotoxic side effects on normal tissue has increasingly become… 
2010
2010
Fragmentation studies and electrospray ionization mass spectrometry of lapachol: protonated, deprotonated and cationized species.
Electrospray ionization mass spectrometric analysis of lapachol (2-hydroxy-3-(3-methyl-2-butenyl)-1,4-naphthoquinone) was… 
2006
2006
Microwave-assisted rapid cyclization of lapachol, a main constituent of Heterophragma adenophyllum
Cyclization reactions of lapachol (1) isolated from Heterophragma adenophyllum have been studied under microwave irradiation… 
Highly Cited
2001
Highly Cited
2001
Molluscicidal and trypanocidal activities of lapachol derivatives.
The activity of the potassium salt of lapachol against the snail Biomphalaria glabrata and its egg masses was tested. The… 
1985
1985
Partial transition-state inhibitors of glyoxalase I from human erythrocytes, yeast and rat liver.
1985
1985
Potentiation of antimetabolite action by uridylate trapping.
1979
1979
Inhibition of synthesis of pyrimidine nucleotides by 2-hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone.
Abstract Dichloroallyl lawsone [2-hydroxy-3-(3,3-dichloroallyl)-1,4-naphthoquinone, NSC 126771] is of interest as an antitumor… 
1977
1977
Schistosomiasis mansoni: blockage of cercarial skin penetration by chemical agents: i. naphthoquinones and derivatives.
1969
1969
The induction of ATP energized mitochondrial volume changes by the combination of the two antitumor age agents showdomycin and lapachol.
The plant substance, lapachol, which is a hydroxyquinone, an antitumor agent, and an uncoupling agent, mimics the behaviour of… 
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