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lactone biosynthetic process

Known as: lactone anabolism, lactone formation, lactone biosynthesis 
The chemical reactions and pathways resulting in the formation of lactone. [GOC:TermGenie]
National Institutes of Health

Papers overview

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2009
2009
The sesquiterpene lactone eupatolide sensitizes breast cancer cells to TRAIL through down-regulation of c-FLIP expression.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising candidate for cancer therapeutics due to its… 
2006
2006
Enantioselective beta-lactone formation from ketene and aldehydes catalyzed by a chiral oxazaborolidine.
[reaction: see text] A novel catalytic system has been developed for the enantioselective synthesis of beta-lactones from ketene… 
2006
2006
High chelation control of three contiguous stereogenic centers in the Reformatsky reactions of indium enolates with alpha-hydroxy ketones: unexpected stereochemistry of lactone formation.
[reaction: see text] A boat-type of chelated bicyclic transition state involving highly diastereoselective construction of three… 
Highly Cited
2005
Highly Cited
2005
Enantioselective enol lactone synthesis under double catalytic conditions.
[reaction: see text] The reaction of dimedone with 1-(2-alkenoyl)-4-bromo-3,5-dimethylpyrazoles in THF, catalyzed by catalytic… 
Highly Cited
2004
Highly Cited
2004
Concise total synthesis of (-)-muricatacin by tandem ring-closing/cross metathesis.
A strategy for the synthesis of chiral 5-(1-hydroxyalk-2-enyl)-5H-furan-2-ones and its application to the total synthesis of… 
1999
1999
Synthesis of Enantio- and Diastereomerically Pure, Tetra- and Penta-Substituted Cyclopentanes by the Desymmetrization of endo-Norborn-5-ene-2,3-dicarboxylic Anhydrides.
The desymmetrization of endo-norborn-5-ene-2,3-dicarboxylic anhydrides by methyl (S)-prolinate followed by ozonolysis of the… 
1998
1998
Synthesis and inhibitory action on HMG-CoA synthase of racemic and optically active oxetan-2-ones (beta-lactones).
1993
1993
The initiation of peptide formation in the biosynthesis of actinomycin.
Highly Cited
1991
Highly Cited
1991
Antibodies to poly[(2----8)-alpha-N-acetylneuraminic acid] and poly[(2----9)-alpha-N-acetylneuraminic acid] are elicited by immunization of mice with Escherichia coli K92 conjugates: potential…
Meningitis and other systemic infections caused by group B Neisseria meningitidis and Escherichia coli K1 remain important… 
1989
1989
Studies on the biosynthesis of corrinoids and porphyrinoids. I. The labeling of oxygen of vitamin B12.
Recently the amide-oxygen has been suggested to participate in the formation of the corrin ring of vitamin B12. To confirm this… 
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