lactone biosynthetic process

Known as: lactone anabolism, lactone formation, lactone biosynthesis 
The chemical reactions and pathways resulting in the formation of lactone. [GOC:TermGenie]
National Institutes of Health

Papers overview

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2011
2011
Nodulation-gene-inducing flavonoids increase overall production of autoinducers and expression of N-acyl homoserine lactone synthesis genes in rhizobia.
Legume-nodulating rhizobia use N-acyl homoserine lactones (AHLs) to regulate several physiological traits related to the… (More)
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2010
2010
UDP-glucuronosyltransferase (UGT) polymorphisms affect atorvastatin lactonization in vitro and in vivo.
The response to statins shows large interpatient variability. Atorvastatin delta-lactone is pharmacologically inactive but has… (More)
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2009
2009
Andrographolide enhances 5-fluorouracil-induced apoptosis via caspase-8-dependent mitochondrial pathway involving p53 participation in hepatocellular carcinoma (SMMC-7721) cells.
Despite recent significant advances in the treatment of human carcinoma (HCC), the results of chemotherapy to date remain… (More)
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2008
2008
Andrographolide sensitizes cancer cells to TRAIL-induced apoptosis via p53-mediated death receptor 4 up-regulation.
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is an important member of the tumor necrosis factor subfamily… (More)
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2006
2006
Critical role of pro-apoptotic Bcl-2 family members in andrographolide-induced apoptosis in human cancer cells.
Andrographolide (Andro), a diterpenoid lactone isolated from a traditional herbal medicine Andrographis paniculata, is known to… (More)
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2003
2003
Detection of secreted peptides by using hypothesis-driven multistage mass spectrometry.
A method is presented for the rapid detection and characterization of trace amounts of peptides secreted from microorganisms… (More)
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Highly Cited
2002
Highly Cited
2002
Long-chain acyl-homoserine lactone quorum-sensing regulation of Rhodobacter capsulatus gene transfer agent production.
Many proteobacteria use acyl-homoserine lactones as quorum-sensing signals. Traditionally, biological detection systems have been… (More)
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Highly Cited
1999
Highly Cited
1999
Characterization of Pseudomonas aeruginosa enoyl-acyl carrier protein reductase (FabI): a target for the antimicrobial triclosan and its role in acylated homoserine lactone synthesis.
The Pseudomonas aeruginosa fabI structural gene, encoding enoyl-acyl carrier protein (ACP) reductase, was cloned and sequenced… (More)
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1992
1992
Immunosuppression by human gangliosides: I. Relationship of carbohydrate structure to the inhibition of T cell responses.
Causes of cellular immunodeficiency frequently associated with cancer remain poorly understood. One possible mechanism is tumor… (More)
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Review
1983
Review
1983
Vitamin D: recent advances.
The field of vitamin D metabolism and mechanism of action has continued to be very active. Autoradiography has shown specific… (More)
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