Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 238,607,850 papers from all fields of science
Search
Sign In
Create Free Account
kethoxal
Known as:
3-ethoxy-2-oxobutyraldehyde
, Chetossale
, 3-ethoxy-1,1-dihydroxy-2-butanone
Expand
An agent that reacts with guanine to create a covalent adduct. In vivo, Kethoxal reacts with 30S ribosomal subunits yielding inactive ribosomes.
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
Broader (2)
Aldehydes
Antiviral Agents
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1984
1984
Probing the conformation of 18S rRNA in yeast 40S ribosomal subunits with kethoxal.
J. Hogan
,
Robin Gutell
,
H. Noller
Biochemistry
1984
Corpus ID: 41622683
Yeast 40S ribosomal subunits have been reacted with kethoxal to probe the conformation of 18S rRNA. Over 130 oligonucleotides…
Expand
1984
1984
Probing the conformation of 26S rRNA in yeast 60S ribosomal subunits with kethoxal.
J. Hogan
,
Robin Gutell
,
H. Noller
Biochemistry
1984
Corpus ID: 25306833
The conformation and accessibility of 26S rRNA in yeast 60S ribosomal subunits were probed with kethoxal. Oligonucleotides…
Expand
1981
1981
Ribonucleic acid-protein cross-linking in Escherichia coli ribosomes: (4-azidophenyl)glyoxal, a novel heterobifunctional reagent.
S. Politz
,
H. Noller
,
Paul D. McWhirter
Biochemistry
1981
Corpus ID: 44700284
We have used the heterobifunctional reagent (4-azidophenyl)glyoxal (APG) to cross-link RNA to protein in Escherichia coli 30S…
Expand
Highly Cited
1978
Highly Cited
1978
Initial reaction of 3-ethyoxy-2-oxobutyraldehyde bis(thiosemicarbazonato) copper(II) with Ehrlich ascites tumor cells.
Daniel T. Minkel
,
D. Petering
Cancer Research
1978
Corpus ID: 20276089
The antineoplastic agent, 3-ethoxy-2-oxobutyraldehyde bis(thiosemicarbazonato) copper(II), undergoes a pseudo-first-order…
Expand
1978
1978
Structure and function of 5S ribosomal ribonucleic acid from Torulopsis utilis. IV. Detection of exposed guanine residues by chemical modification with kethoxal.
K. Nishikawa
,
Shosuke Takemura
Journal of Biochemistry (Tokyo)
1978
Corpus ID: 5930793
The reaction of Torulopsis (Candida) utilis 5S ribosomal RNA with kethoxal (beta-ethoxy-alpha-ketobutyraldehyde) was studied in…
Expand
1978
1978
Nucleotide sequences of accessible regions of 23S RNA in 50S ribosomal subunits.
W. Herr
,
Harry F. Noller
Biochemistry
1978
Corpus ID: 25560396
Nucleotide sequences around kethoxal-reactive guanine residues of 23S RNA in 50S ribosomal subunits have been determined. By use…
Expand
1976
1976
Technetium-99m-kethoxal-bis(thiosemicarbazone), an uncharged complex with a tetravalent 99mTc state, and its excretion into the bile.
Akira Yokoyama
,
Y. Terauchi
,
Kazuko Horiuchi
,
Hisashi Tanaka
,
T. Odori
Journal of Nuclear Medicine
1976
Corpus ID: 2766972
Technetium-99m-kethoxal-bis (thiosemicarbazone) complex (99mTc-KTS), a potentially useful radiopharmaceutical for…
Expand
Highly Cited
1973
Highly Cited
1973
Effect of heavy metals on the in vitro cytotoxicity of 3-ethoxy-2-oxobutyraldehyde bis (thiosemicarbazone) and related compounds.
G. J. Van Glessen
,
J. A. Crim
,
D. Petering
,
H. Petering
Journal of the National Cancer Institute
1973
Corpus ID: 44312886
1965
1965
Kethoxal bis(thiosemicarbazone). II. Toxic and pathologic effects.
E. Mihich
,
C. L. Simpson
,
Anda I. Mulhern
Cancer Research
1965
Corpus ID: 16575698
The marked activity of kethoxal bis(thiosemicarbazone) against several experimental tumors prompted the preclinical pharmacologic…
Expand
1965
1965
Kethoxal bis(thiosemicarbazone). I. Effects against experimental tumors.
E. Mihich
,
C. A. Nichol
Cancer Research
1965
Corpus ID: 9979600