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kendomycin

 
National Institutes of Health

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2016
2016
Purpose The emergence of bacteria that are resistant to many currently used drugs emphasizes the need to discover and develop new… Expand
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2014
2014
In an attempt to study the ability of the latest generation of alkyne metathesis catalysts to process sterically hindered… Expand
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2010
2010
One-step formation of the ansa-skeleton realized the synthesis of kendomycin, an ansa-type quinone methide. The Fischer carbene… Expand
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2010
2010
Two convergent total syntheses of the ansa-polyketide (-)-kendomycin (1) are described. The syntheses benefit from the use of… Expand
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2008
2008
Kendomycin is a bioactive polyketide that is produced by various Streptomyces strains. It displays strong antibiotic activities… Expand
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2008
2008
The kendomycin skeleton was prepared by a highly convergent strategy in which the benzofuran fragment and the acyclic iodide… Expand
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2008
2008
The cytotoxic macrolide kendomycin was identified as a ligand of Bcl-xl, an anti-apoptotic member of the Bcl-2 protein family… Expand
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2007
2007
The macrocyclic polyketide kendomycin exhibits antiosteoporotic and antibacterial activity, as well as strong cytotoxicity… Expand
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2004
2004
Kendomycin, also known as (-)-TAN 2162, is a novel polyketide-derived ansamycin isolated from Streptomyces sp., which exhibits… Expand
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2004
2004
The convergent synthesis of a benzofuran analog of the carbacyclic ansa compound kendomycin has been achieved by assembling three… Expand
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