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kahweol

National Institutes of Health

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Diterpenes

Papers overview

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2019
2019
Mitochondrial Protection Promoted by the Coffee Diterpene Kahweol in Methylglyoxal-Treated Human Neuroblastoma SH-SY5Y Cells
The coffee diterpene kahweol (KW; C20H26O3) is a cytoprotective agent exhibiting potent antioxidant actions, as demonstrated in… 
2014
2014
Anti‐Proliferative Properties of Kahweol in Oral Squamous Cancer Through the Regulation Specificity Protein 1
Kahweol, the coffee‐specific deterpene, has been shown to have potential anti‐cancer effects against several cancers. However… 
2011
2011
Melatonin sensitizes Caki renal cancer cells to kahweol‐induced apoptosis through CHOP‐mediated up‐regulation of PUMA
Abstract:  Melatonin has recently gained attention as a regulator of biologic processes in addition to its effects on circadian… 
2010
2010
The coffee diterpene kahweol sensitizes TRAIL-induced apoptosis in renal carcinoma Caki cells through down-regulation of Bcl-2 and c-FLIP.
2008
2008
The multifaceted mechanisms for coffee's anti-tumorigenic effect on liver.
2003
2003
Coffee diterpenes prevent benzo[a]pyrene genotoxicity in rat and human culture systems.
Highly Cited
2002
Highly Cited
2002
Enhancement of the chemoprotective enzymes glucuronosyl transferase and glutathione transferase in specific organs of the rat by the coffee components kahweol and cafestol
Abstract. The coffee components kahweol and cafestol (K/C) have been reported to protect the colon and other organs of the rat… 
1996
1996
Placental glutathione S-transferase (GST-P) induction as a potential mechanism for the anti-carcinogenic effect of the coffee-specific components cafestol and kahweol.
The coffee specific diterpenes cafestol and kahweol (C + K) have been reported to be anti-carcinogenic in several animal models… 
1991
1991
Kahweol and cafestol: inhibitors of hamster buccal pouch carcinogenesis.
Kahweol and cafestol, two compounds extracted from green coffee beans, were tested for cancer chemopreventive activity. For the… 
1986
1986
Characterization of bacterial mutagenicity mediated by 13-hydroxy-ent-kaurenoic acid (steviol) and several structurally-related derivatives and evaluation of potential to induce glutathione S…
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