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isometronidazole

Known as: 1-(2'-hydroxyethyl)-2-methyl-4-nitroimidazole, iso-metronidazole 
National Institutes of Health

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Metronidazole
analogs & derivatives

Papers overview

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2004
2004
Effect of the Hypoxic Cell Sensitizer Isometronidazole on Local Control of Two Human Squamous Cell Carcinomas after Fractionated Irradiation
Background and Purpose:Hypoxia of clonogenic tumor cells is a major reason for radioresistance and hence local failure in… 
1992
1992
Pharmacokinetics of isometronidazole. Basic model and estimation of the kinetic parameters from experimental data.
For the optimal timing of application of radiosensitizers in a course of radiotherapy it is important to know the sensitizer… 
1991
1991
[The immediate results of the use of isometronidazole in the combination therapy of patients with lung cancer].
The paper is devoted to assessment of isometronidazole tolerance, used as a radiosensitizer for preoperative irradiation of lung… 
1991
1991
[The radiation-sensitizing effect of isometronidazole following its intravesical application in bladder carcinoma. A clinical phase-II study].
The radiosensitizing efficacy of iso-metronidazole, a 4-nitroimidazole derivative, was evaluated in a prospective clinical phase… 
1988
1988
[The pharmacokinetics of 2-methyl-4-nitroimidazole-1-ethanol (isometronidazole) in man].
2 and 4 g isometronidazole, respectively, were administered to two groups of 6 healthy male volunteers (21-29 years, 62-93 kg… 
1986
1986
[Radiosensitizing and toxic action of metronidazole and isometronidazole (1-(2-hydroxyethyl)-2-methyl-4-nitroimidazole) on the cells of Ehrlich ascites cancer and hemoblastosis La in vitro].
A study was made of Ehrlich ascites tumor growth and life span of mice bearing hemoblastosis La after inoculation of tumor cells… 
1986
1986
[Radiosensitizing and toxic action of metronidazole and isometronidazole (1-(2-hydroxyethyl)-2-methyl-4-nitroimidazole) on the cells of Ehrlich ascites cancer and hemoblastosis La in vitro].
: A study was made of Ehrlich ascites tumor growth and life span of mice bearing hemoblastosis La after inoculation of tumor… 
1985
1985
[Tissue distribution of iso-metronidazole and metronidazole in tumor-bearing C3H inbred mice].
Among the group of nitroimidazole radiosensitizers, predominantly misonidazole and metronidazole have so far been submitted to an… 
1981
1981
[Comparative studies on the radiosensitizing action of 4-nitroimidazole and metronidazole (author's transl)].
After the 2-nitroimidazole derivatives, misonidazole, and the 5-nitroimidazole derivative, metronidazole, had been tried in… 
1968
1968
Urinary excretion of metronidazole and isometronidazole in the rat.
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