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Metronidazole

Known as: 1-(?-ethylol)-2-methyl-5-nitro-3-azapyrrole, 2-methyl-1-(2-hydroxyethyl)-5-nitroimidazole, Metronidazol 
A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un… 
National Institutes of Health

Related topics

Related topics

42 relations

Narrower (16)

1-methyl-5-sulfonamide-4-nitroimidazole2-hydroxymethyl-1-methyl-5-nitroimidazoleCervugidClont
AmebiasisBacterial InfectionsIn BloodMETRONIDAZOLE 500 mg ORAL POWDER [FISH ZOLE FORTE]

Broader (4)

Anti-Bacterial AgentsAnti-Infective AgentsAntiprotozoal AgentsImidazoles

Papers overview

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Highly Cited
1984
Highly Cited
1984
Subgingival metronidazole in dialysis tubing and subgingival chlorhexidine irrigation in the control of chronic inflammatory periodontal disease.
The present investigation compared subgingival metronidazole in dialysis tubing and subgingival chlorhexidine irrigation in the… 
1984
1984
Nitroaromatic radiation sensitizers substitute for oxygen in neocarzinostatin-induced DNA damage.
The ability of neocarzinostatin (NCS) chromophore to damage DNA, as manifested by strand breaks and base release, is markedly… 
Highly Cited
1983
Highly Cited
1983
Purine salvage networks in Giardia lamblia
Purine metabolism in Giardia lamblia was investigated by monitoring incorporation of radiolabeled precursors into purine… 
Highly Cited
1981
Highly Cited
1981
Liquid chromatographic assay for metronidazole and tinidazole: pharmacokinetic and metabolic studies in human subjects
We developed methods for measuring metronidazole, its two major metabolites, and tinidazole in serum and urine. After treatment… 
Highly Cited
1979
Highly Cited
1979
The effect of metronidazole on the development of plaque and gingivitis in the beagle dog.
The present investigation was performed in order to assess if the administration of metronidazole changed the composition of… 
Highly Cited
1977
Highly Cited
1977
Susceptibility of Anaerobic Bacteria to Metronidazole, Ornidazole, and Tinidazole and Routine Susceptibility Testing by Standardized Methods
A total of 114 strains of anaerobic bacteria were examined for their susceptibility to metronidazole, ornidazole, and tinidazole… 
Highly Cited
1975
Highly Cited
1975
Selective radiosensitization of the hypoxic cells of mouse tumors with the nitroimidazoles metronidazole and Ro 7-0582.
BROWN, J. M. Selective Radiosensitization of the Hypoxic Cells of Mouse Tumors with the Nitroimidazoles Metronidazole and Ro 7… 
Highly Cited
1975
Highly Cited
1975
Tests of two electron-affinic radiosensitizers in vivo using regrowth of an experimental carcinoma.
Two electron-affinic nitroimidazoles have been investigated as potential radiosensitizers using tumor regrowth as a measure of… 
1975
1975
Electron-affinic sensitization. VI. A pulse radiolysis and ESR comparison of some 2- and 5-nitroimidazoles.
1974
1974
Tumor and normal tissue response to metronidazole and irradiation in mice.
The effects of metronidazole, which selectively sensitizes hypoxic cells, on the radiation response of C3H mouse mammary…