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Metronidazole

Known as: 1-(?-ethylol)-2-methyl-5-nitro-3-azapyrrole, 2-methyl-1-(2-hydroxyethyl)-5-nitroimidazole, Metronidazol 
A synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un… 
National Institutes of Health

Related topics

Related topics

42 relations

Narrower (16)

1-methyl-5-sulfonamide-4-nitroimidazole2-hydroxymethyl-1-methyl-5-nitroimidazoleCervugidClont
AmebiasisBacterial InfectionsIn BloodMETRONIDAZOLE 500 mg ORAL POWDER [FISH ZOLE FORTE]

Broader (4)

Anti-Bacterial AgentsAnti-Infective AgentsAntiprotozoal AgentsImidazoles

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2005
Review
2005
Perirectal haematoma and hypovolaemic shock after rectal stapled mucosectomy for haemorrhoids
Dear Editor: After a systematic review of rectal stapled mucosectomy (Longo’s procedure) reports, the final conclusion of… 
1985
1985
Occurrence of three cases of carcinoma in individuals with Crohn's disease treated with metronidazole.
Controversy exists regarding the safety of metronidazole. Experimental studies have suggested both a carcinogenic and mutagenic… 
Highly Cited
1984
Highly Cited
1984
Subgingival metronidazole in dialysis tubing and subgingival chlorhexidine irrigation in the control of chronic inflammatory periodontal disease.
The present investigation compared subgingival metronidazole in dialysis tubing and subgingival chlorhexidine irrigation in the… 
1981
1981
The effect of metronidazole and sulfasalazine on the fecal flora in patients with Crohn's disease.
Twenty patients with Crohn's disease were treated with metronidazole (Flagyl) or sulfasalazine (Salazopyrin). Before and during… 
Highly Cited
1979
Highly Cited
1979
The effect of metronidazole on the development of plaque and gingivitis in the beagle dog.
The present investigation was performed in order to assess if the administration of metronidazole changed the composition of… 
1978
1978
Actinomycin Biosynthesis by Protoplasts Derived from Streptomyces parvulus
Conditions are described for the formation of protoplasts from Streptomyces parvulus that are able to synthesize actinomycin D de… 
Highly Cited
1977
Highly Cited
1977
Susceptibility of Anaerobic Bacteria to Metronidazole, Ornidazole, and Tinidazole and Routine Susceptibility Testing by Standardized Methods
A total of 114 strains of anaerobic bacteria were examined for their susceptibility to metronidazole, ornidazole, and tinidazole… 
1975
1975
Electron-affinic sensitization. VI. A pulse radiolysis and ESR comparison of some 2- and 5-nitroimidazoles.
1974
1974
Tumor and normal tissue response to metronidazole and irradiation in mice.
The effects of metronidazole, which selectively sensitizes hypoxic cells, on the radiation response of C3H mouse mammary… 
Highly Cited
1974
Highly Cited
1974
Hypoxic cell radiosensitizers: comparative tests of some electron affinic compounds using epidermal cell survival in vivo.
The ability of certain electron affinic compounds to sensitize hypoxic cells to radiation has been tested using an in vivo assay…