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isofagomine

Known as: 5-hydroxymethyl-3,4-piperidinediol, iso-fagomine 
National Institutes of Health

Related topics

Related topics

2 relations

Narrower (1)

4-epi-isofagomine

Broader (1)

Imino Pyranoses

Papers overview

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2018
2018
Gintonin, a Ginseng-Derived Exogenous Lysophosphatidic Acid Receptor Ligand, Protects Astrocytes from Hypoxic and Re-oxygenation Stresses Through Stimulation of Astrocytic Glycogenolysis
Astrocytes are a unique brain cell-storing glycogen and express lysophosphatidic acid (LPA) receptors. Gintonin is a ginseng… 
2017
2017
Glucosylceramide metabolism: from 3D structure to the development of selective chemical probes
Gaucher's disease, the most prevalent of the lysosomal storage disorders, is caused by insufficient lysosomal glucocerebrosidase… 
2015
2015
A fluorescence study of isofagomine protonation in β-glucosidase.
N-(10-Chloro-9-anthracenemethyl)isofagomine 5 and N-(10-chloro-9-anthracenemethyl)-1-deoxynojirimycin 6 were prepared, and their… 
2011
2011
Docking and SAR studies of D- and L-isofagomine isomers as human β-glucocerebrosidase inhibitors.
2007
2007
Tartrate salt of isofagomine and methods of use thereof
2005
2005
Synthesis and evaluation of the glycosidase inhibitory activity of 5-hydroxy substituted isofagomine analogues.
An efficient strategy for the synthesis of 5-hydroxy substituted isofagomine analogues and , having both -CH2OH/CH3 and -OH… 
2004
2004
Design and synthesis of 2-acetamidomethyl derivatives of isofagomine as potential inhibitors of human lysosomal beta-hexosaminidases.
As part of a program towards the development of specific inhibitors of human lysosomal beta-hexosaminidase for use as chemical… 
2003
2003
A xylobiose-derived isofagomine lactam glycosidase inhibitor binds as its amide tautomer.
The atomic-resolution structure of a xylobiose-derived isofagomine lactam in complex with the xylanase Xyn10A from Streptomyces… 
2002
2002
A norbornyl route to some novel seven-membered iminocyclitols
2001
2001
Efficient synthesis of isofagomine and noeuromycin.
Starting from D-arabinose the synthesis of the very strong glycosidase inhibitors isofagomine (2) and noeuromycin (3) was… 
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