isocarbostyril
National Institutes of Health
Papers overview
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The isocarbostyril alkaloid narciclasine, also known as lycoricidinol, was discovered in Narcissus species (Amaryllidaceae) in…
A series of new natural product skeleton based 3-(halobenzyl)isocarbostyrils (2a–2i), were designed and synthesized to examine…
Narciclasine (1) is a plant growth regulator that has been previously demonstrated to be proapoptotic to cancer cells at high…
Hydrophobic base analogues (HBAs) have shown great promise for the expansion of the chemical and coding potential of nucleic…
Plants of the Amaryllidaceae family have been under intense scrutiny for the presence of the specific metabolites responsible for…
Our study has shown that the Amaryllidaceae isocarbostyril narciclasine induces marked apoptosis-mediated cytotoxic effects in…
As an extension of structure-activity relationship studies of pancratistatin (1), various techniques were first evaluated for…
A five-step, atom-efficient synthesis of the Galanthan tetracyclic skeleton has been developed. The key step is an unusual…
The bulbs of Hymenocallis littoralis, collected in Hawaii and horticulturally grown in Arizona, and bulbs of Hymenocallis…