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isocarbostyril

 
National Institutes of Health

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1 relation

Broader (1)

Isoquinolines

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Synthesis and effect of substituent position on anti-inflammatory activity of 3-(halobenzyl)isocarbostyrils
A series of new natural product skeleton based 3-(halobenzyl)isocarbostyrils (2a–2i), were designed and synthesized to examine… Expand
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Highly Cited
2009
Highly Cited
2009
Structure-activity relationship analysis of novel derivatives of narciclasine (an Amaryllidaceae isocarbostyril derivative) as potential anticancer agents.
Narciclasine (1) is a plant growth regulator that has been previously demonstrated to be proapoptotic to cancer cells at high… Expand
Highly Cited
2009
Highly Cited
2009
Evolving a polymerase for hydrophobic base analogues.
Hydrophobic base analogues (HBAs) have shown great promise for the expansion of the chemical and coding potential of nucleic… Expand
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Highly Cited
2008
Highly Cited
2008
Anticancer evaluation of structurally diverse Amaryllidaceae alkaloids and their synthetic derivatives
Plants of the Amaryllidaceae family have been under intense scrutiny for the presence of the specific metabolites responsible for… Expand
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Highly Cited
2007
Highly Cited
2007
The Amaryllidaceae isocarbostyril narciclasine induces apoptosis by activation of the death receptor and/or mitochondrial pathways in cancer cells but not in normal fibroblasts.
Our study has shown that the Amaryllidaceae isocarbostyril narciclasine induces marked apoptosis-mediated cytotoxic effects in… Expand
2006
2006
Isolation and structural modification of 7-deoxynarciclasine and 7-deoxy-trans-dihydronarciclasine.
As an extension of structure-activity relationship studies of pancratistatin (1), various techniques were first evaluated for… Expand
2004
2004
A photochemical approach to the Galanthan ring system.
A five-step, atom-efficient synthesis of the Galanthan tetracyclic skeleton has been developed. The key step is an unusual… Expand
Highly Cited
1993
Highly Cited
1993
Antineoplastic agents, 256. Cell growth inhibitory isocarbostyrils from Hymenocallis.
The bulbs of Hymenocallis littoralis, collected in Hawaii and horticulturally grown in Arizona, and bulbs of Hymenocallis… Expand
1989
1989
Theoretical approach to the problem of finding effective luminophors in the isocarbostyril series
It has been established that the main reason for the low fluorescence quantum yield of unsubstituted isocarbostyril (I) is the… Expand
1976
1976
[Studies on the synthesis of isocarbostyril derivatives. (1). A novel synthesis of isocarbostyril derivatives and synthesis of protoberberine and dibenzoquinolizine derivatives (author's transl)].
 
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