iratumumab

Known as: MDX060 monoclonal antibody, Monoclonal Antibody MDX-060, 5F11 monoclonal antibody 
A fully human monoclonal antibody with potential antineoplastic activity. MDX-060 is a fully humanized antibody that targets CD30, a member of the… (More)
National Institutes of Health

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MDX-060

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Monoclonal Antibodies
antigen binding

Papers overview

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2017
2017
Specific ADAM10 inhibitors localize in exosome-like vesicles released by Hodgkin lymphoma and stromal cells and prevent sheddase activity carried to bystander cells
Shedding of ADAM10 substrates, like TNFα, MICA or CD30, is reported to affect both anti-tumor immune response and antibody-drug… (More)
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2009
2009
In vitro and in vivo characterization of MDX-1401 for therapy of malignant lymphoma.
PURPOSE This study was undertaken to evaluate the effects of MDX-1401, a nonfucosylated fully human monoclonal antibody that… (More)
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2008
2008
Gateways to clinical trials.
Gateways to clinical trials is a guide to the most recent trials in current literature and congresses. The data in the following… (More)
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Review
2007
Review
2007
Monoclonal Antibodies in the Treatment of Non-Hodgkin’s Lymphoma
Antibody-based therapeutic approaches have had a significant impact in the treatment of non-Hodgkin’s lymphoma (NHL). Rituximab’s… (More)
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