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iodine I 123 monoclonal antibody 81C6

Known as: 81C6, I 123 Monoclonal Antibody 81C6, iodine I 123 MOAB 81C6 
A radioimmunoconjugate of a IgG2 monoclonal antibody (MoAb) 81C6 labeled with iodine 123 (I-123). MoAb 81C6 recognizes the extracellular matrix… 
National Institutes of Health

Papers overview

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1999
1999
Dosimetry of 131I-labeled 81C6 monoclonal antibody administered into surgically created resection cavities in patients with malignant brain tumors.
UNLABELLED The objective of this study was to perform the dosimetry of 131I-labeled 81C6 monoclonal antibody (MAb) in patients… 
1996
1996
Chimeric anti-tenascin antibody 81C6: increased tumor localization compared with its murine parent.
Highly Cited
1993
Highly Cited
1993
Distribution and dosimetry of I-123-labeled monoclonal antibody 81C6 in patients with anaplastic glioma.
RATIONALE AND OBJECTIVES Monoclonal antibody 81C6 reacts with the extracellular matrix antigen, tenascin, present on gliomas and… 
Highly Cited
1989
Highly Cited
1989
Enhanced tumor localization and in vivo stability of a monoclonal antibody radioiodinated using N-succinimidyl 3-(tri-n-butylstannyl)benzoate.
Loss of radiolabel after in vivo administration of labeled monoclonal antibodies (MAbs) to cancer patients is a likely cause of… 
Highly Cited
1988
Highly Cited
1988
Treatment of intracranial human glioma xenografts with 131I-labeled anti-tenascin monoclonal antibody 81C6.
Lack of tumor specificity renders current modalities for treating malignant glioma ineffective. The administration of 131I… 
1988
1988
The localisation of radiolabelled murine monoclonal antibody 81C6 and its Fab fragment in human glioma xenografts in athymic mice.
The localisation of the radioiodinated Fab fragment of monoclonal antibody (Mab) 81C6, reactive with a glioma-associated… 
Highly Cited
1987
Highly Cited
1987
Distribution of Type VI Collagen in Human Gliomas: Comparison with Fibronectin and Glioma‐Mosenchymal Matrix Glycoprotein
The distribution of type VI collagen was examined immunohistochemically in normal tissues and in 24 human gliomas and six… 
1987
1987
Comparison of monoclonal antibody delivery to intracranial glioma xenografts by intravenous and intracarotid administration.
Monoclonal antibody 81C6, which is directed against a human gliomamesenchymal extracellular matrix antigen, was used to evaluate… 
1986
1986
In vivo imaging of intracranial human glioma xenografts comparing specific with nonspecific radiolabeled monoclonal antibodies.
Current diagnostic and therapeutic modalities for malignant human gliomas are largely nonspecific. The development of monoclonal… 
Highly Cited
1984
Highly Cited
1984
Monoclonal antibody localization in subcutaneous and intracranial human glioma xenografts: paired-label and imaging analysis.
The murine antiglioma monoclonal antibody 81C6 has been shown to specifically localize in U-251 MG and D-54 MG human glioma… 
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