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- Publications
- Influence
Response criteria for phase II studies of supratentorial malignant glioma.
- D. Macdonald, T. Cascino, S. Schold, J. Cairncross
- Medicine
- Journal of clinical oncology : official journal…
- 1 July 1990
We suggest "new" response criteria for phase II studies of supratentorial malignant glioma and favor rigorous criteria similar to those in medical oncology, with important modifications. Four… Expand
Placebo-controlled trial of safety and efficacy of intraoperative controlled delivery by biodegradable polymers of chemotherapy for recurrent gliomas
- H. Brem, S. Piantadosi, P. Burger, M. Walker, S. Schold
- Medicine
- The Lancet
- 22 April 1995
Chemotherapy for brain tumours has been limited because of difficulty in achieving adequate exposure to the tumour without systemic toxicity. We have developed a method for local sustained release of… Expand
Combination chemotherapy and radiotherapy for primary central nervous system lymphoma: Radiation Therapy Oncology Group Study 93-10.
- L. DeAngelis, W. Seiferheld, S. Schold, B. Fisher, C. Schultz
- Medicine
- Journal of clinical oncology : official journal…
- 15 December 2002
PURPOSE
Primary CNS lymphoma (PCNSL) is an aggressive primary brain tumor. Cranial irradiation alone rarely results in long-term disease control or prolonged survival. We prospectively studied the… Expand
Anti‐Ri: An antibody associated with paraneoplastic opsoclonus and breast cancer
- F. Antonio Luque, Henry M. Furneaux, +10 authors Jerome B. Posner
- Medicine
- Annals of neurology
- 1 March 1991
The serum and cerebrospinal fluid (CSF) of 8 women with ataxia, 6 of whom also had eye movement abnormalities believed to be opsoclonus, were found to contain a highly specific antineuronal antibody… Expand
Increasing incidence of primary brain lymphoma in the US
- N. Eby, S. Grufferman, C. M. Flannelly, S. Schold, F. Vogel, P. Burger
- Medicine
- Cancer
- 1 December 1988
There have been a number of clinical reports suggesting an increasing incidence of primary brain lymphoma unrelated to acquired immune deficiency syndrome (AIDS) and organ transplantation. To… Expand
Interstitial chemotherapy with drug polymer implants for the treatment of recurrent gliomas.
- H. Brem, M. S. Mahaley, +7 authors J. Cozzens
- Medicine
- Journal of neurosurgery
- 1 March 1991
Malignant gliomas have been difficult to treat with chemotherapy. The most effective agent, BCNU (carmustine), has considerable systemic toxicity and a short half-life in serum. To obviate these… Expand
High-dose oral tamoxifen, a potential multidrug-resistance-reversal agent: phase I trial in combination with vinblastine.
- D. Trump, D. Smith, +6 authors R. Fine
- Medicine
- Journal of the National Cancer Institute
- 2 December 1992
BACKGROUND
P-glycoprotein mediates resistance to natural-product anti-neoplastic agents like vinblastine through an active transport process resulting in reduced intracellular concentration of these… Expand
Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study.
- K. Jaeckle, H. Eyre, +7 authors S. Schold
- Medicine
- Journal of clinical oncology : official journal…
- 1 October 1998
PURPOSE
Prior studies show that increased levels of the DNA repair protein O6 methylguanine-DNA methyltransferase (MGMT), also referred to as O6-alkylguanine-DNA alkyltransferase (AGT) correlate with… Expand
Multifaceted resistance of gliomas to temozolomide.
- D. B. Bocangel, S. Finkelstein, S. Schold, K. Bhakat, S. Mitra, D. Kokkinakis
- Biology, Medicine
- Clinical cancer research : an official journal of…
- 1 August 2002
PURPOSE AND EXPERIMENTAL DESIGN
The contributions of O6-methylguanine-DNA-methyltransferase(MGMT), p53 status, mismatch repair, and apoptotic response to the resistance of glial tumors to… Expand
Fibronectin and glial fibrillary acidic protein expression in normal human brain and anaplastic human gliomas.
- T. R. Jones, E. Ruoslahti, S. Schold, D. Bigner
- Medicine
- Cancer research
- 1982
Abstract The expression of fibronectin (FN), an extracellular matrix glycoprotein with adhesive and opsonic properties, was examined in normal and neoplastic human central nervous system tissues. In… Expand