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involucrin

Known as: Benzoic acid, 3,4,5-trimethoxy-, 4-(acetyloxy)-6,10-dimethyl-3-(1-methylethyl)-11-oxabicyclo(8.1.0)undec-6-en-2-yl ester 
Involucrin (585 aa, ~68 kDa) is encoded by the human IVL gene. This protein plays a role in the keratinization of stratified squamous epithelia.
National Institutes of Health

Related topics

Related topics

8 relations

Broader (2)

IVL geneProtein Precursors
KeratinStratified squamous epitheliumStructural ProteinStructural gene

Papers overview

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2004
2004
Expression of EGF receptor, involucrin, and cytokeratins in basal cell carcinomas and squamous cell, carcinomas of the skin
SummaryThe distribution of several markers of keratinocyte differentiation was studied in normal epidermis, basal cell carcinomas… 
2003
2003
Histopathological and immunohistochemical assessment of acquired ichthyosis in patients with human T‐cell lymphotropic virus type I‐associated myelopathy
Background  Patients with human T‐cell lymphotropic virus type I (HTLV‐I)‐associated myelopathy frequently display cutaneous… 
Highly Cited
1993
Highly Cited
1993
Analysis of the 5'-upstream promoter region of human involucrin gene: activation by 12-O-tetradecanoylphorbol-13-acetate.
Involucrin is one of the precursor proteins of keratinocyte cornified envelope. Although the formation of the cornified envelope… 
1993
1993
Calcium modulates cornified envelope formation, involucrin content, and transglutaminase activity in cultured human ectocervical epithelial cells.
The entrance to the cervical canal, the ectocervix, is covered by a stratified squamous epithelium. In the present study we… 
1989
1989
Heterogeneity of keratin expression in epithelial tumor cells of adenolymphoma in paraffin sections.
1988
1988
Keratin and involucrin immunohistochemistry of nasopharyngeal carcinoma
Forty nasopharyngeal carcinomas (NPC) were studied by immunohistochemistry using an antibody to involucrin and the following… 
1987
1987
Involucrin expression in skin appendage tumours
The expression of involucrin was examined in 23 skin tumours of hair follicle origin, 17 tumours of sweat gland origin and three… 
1987
1987
Keratin and involucrin in preneoplastic and neoplastic lesions. Distribution in the nasal mucosa of nickel workers.
Nasal mucosal biopsy specimens encompassing normal and pathological epithelia were obtained from nickel workers, a population… 
Highly Cited
1985
Highly Cited
1985
Modulation of the terminal differentiation of human squamous carcinoma cells in vitro by all-trans-retinoic acid.
A malignant human cell line (SqCC/Y1) derived from a squamous carcinoma of the buccal mucosa is described. It formed a stratified… 
Highly Cited
1984
Highly Cited
1984
Keratolinin: the soluble substrate of epidermal transglutaminase from human and bovine tissue.
Substrates of human and bovine epidermal transglutaminase (glutaminyl-peptide gamma-glutamyltransferase, R-glutaminyl-peptide… 
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