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investigational monitoring program
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investigational
National Institutes of Health
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Highly Cited
2013
Highly Cited
2013
Immunogenicity and safety of an investigational multicomponent, recombinant, meningococcal serogroup B vaccine (4CMenB) administered concomitantly with routine infant and child vaccinations: results…
T. Vesikari
,
S. Esposito
,
+5 authors
A. Kimura
The Lancet
2013
Corpus ID: 46157377
Highly Cited
2010
Highly Cited
2010
Cell and gene therapies: moving from research to clinic
D. Stroncek
,
R. Puri
Journal of Translational Medicine
2010
Corpus ID: 215310167
Editorial Cell and gene therapy clinical trials began more than 40 years ago. At some institutions cellular therapy laboratories…
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Highly Cited
2006
Highly Cited
2006
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer—Part 1
S. Sagar
,
D. Yance
,
R. Wong
Current Oncology
2006
Corpus ID: 54467469
An integrative approach for managing a patient with cancer should target the multiple biochemical and physiologic pathways that…
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Highly Cited
2002
Highly Cited
2002
Role of body surface area in dosing of investigational anticancer agents in adults, 1991-2001.
S. Baker
,
J. Verweij
,
+4 authors
A. Sparreboom
Journal of the National Cancer Institute
2002
Corpus ID: 32841667
The prescribed dose of anticancer agents is most commonly calculated using body surface area as the only independent variable…
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Highly Cited
2000
Highly Cited
2000
Symptom reduction and suicide risk in patients treated with placebo in antidepressant clinical trials: an analysis of the Food and Drug Administration database.
Arif Khan
,
Heather A. Warner
,
W. Brown
Archives of General Psychiatry
2000
Corpus ID: 38253092
The assumption that depressed patients who are assigned to placebo in antidepressant clinical trials are exposed to substantial…
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Highly Cited
1998
Highly Cited
1998
Safety and Immunogenicity of Heptavalent Pneumococcal Vaccine Conjugated to CRM197 in United States Infants
M. Rennels
,
K. Edwards
,
+7 authors
A. Kimura
Pediatrics
1998
Corpus ID: 43001699
Objective. To determine the safety and immunogenicity of heptavalent pneumococcal saccharide vaccine (serotypes 4, 6B, 9V, 14…
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Highly Cited
1997
Highly Cited
1997
Double-blind vaccine-controlled randomised efficacy trial of an investigational Shigella sonnei conjugate vaccine in young adults
D. Cohen
,
S. Ashkenazi
,
+14 authors
J. Robbins
The Lancet
1997
Corpus ID: 43558072
Highly Cited
1993
Highly Cited
1993
Effects of IL-12 on the generation of cytotoxic activity in human CD8+ T lymphocytes.
P. Mehrotra
,
D. Wu
,
J. A. Crim
,
Howard S. Mostowski
,
Jay P. Siegel
Journal of Immunology
1993
Corpus ID: 26111595
We have studied the effects of human rIL-12 on the proliferation and generation of cytotoxic activity in human CTL precursors…
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Highly Cited
1984
Highly Cited
1984
Informed consent for investigational chemotherapy: patients' and physicians' perceptions.
D. Penman
,
J. Holland
,
+5 authors
R. Cherry
Journal of Clinical Oncology
1984
Corpus ID: 34433011
One hundred forty-four patients and 68 physicians at three cancer centers were studied for their perceptions of the consent…
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Highly Cited
1981
Highly Cited
1981
Pharmacokinetics of ceftriaxone in humans
I. Patel
,
S. Chen
,
+4 authors
S. A. Kaplan
Antimicrobial Agents and Chemotherapy
1981
Corpus ID: 10489653
Pharmacokinetics of the investigational cephalosporin ceftriaxone were studied after 30-min intravenous infusions of three…
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