interleukin-23 receptor activity

Known as: IL-23 receptor activity, IL-23R 
Combining with interleukin-23 and transmitting the signal from one side of the membrane to the other to initiate a change in cell activity. [GOC:jl… (More)
National Institutes of Health

Related topics

Related topics

3 relations
IL23R gene

Narrower (1)

interleukin-23 binding activity

Broader (1)

interleukin-23-mediated signaling pathway

Papers overview

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Highly Cited
2012
Highly Cited
2012
The aryl hydrocarbon receptor regulates gut immunity through modulation of innate lymphoid cells.
Innate lymphoid cells (ILCs) expressing the nuclear receptor RORγt are essential for gut immunity presumably through production… (More)
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Highly Cited
2012
Highly Cited
2012
Enrichment of circulating interleukin-17-secreting interleukin-23 receptor-positive γ/δ T cells in patients with active ankylosing spondylitis.
OBJECTIVE Ankylosing spondylitis (AS) is a common inflammatory arthritis affecting primarily the axial skeleton. IL23R is… (More)
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Highly Cited
2011
Highly Cited
2011
Cutting edge: crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria.
We have shown previously that peripheral lymph node-resident retinoic acid receptor-related orphan receptor γt(+) NK1.1… (More)
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Highly Cited
2010
Highly Cited
2010
Innate lymphoid cells drive IL-23 dependent innate intestinal pathology
The key role of interleukin (IL)-23 in the pathogenesis of autoimmune and chronic inflammatory disorders is supported by the… (More)
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2010
2010
IL-23R gene confers susceptibility to Behcet's disease in a Chinese Han population.
PURPOSE IL-23 has been shown to be involved in the pathogenesis of Behcet's disease (BD) through promoting IL-17 production. This… (More)
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Highly Cited
2008
Highly Cited
2008
Association of interleukin-23 receptor variants with ankylosing spondylitis.
OBJECTIVE Recent studies have shown that a nonsynonymous single-nucleotide polymorphism (SNP) (Arg381Gln; rs11209026) in the… (More)
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Highly Cited
2008
Highly Cited
2008
Interleukin (IL)-23 receptor is a major susceptibility gene for Graves' ophthalmopathy: the IL-23/T-helper 17 axis extends to thyroid autoimmunity.
CONTEXT IL-23 and its receptor (IL-23R) guide T cells toward the T-helper 17 phenotype. IL-23R single nucleotide polymorphisms… (More)
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Highly Cited
2007
Highly Cited
2007
IL-23 receptor (IL-23R) gene protects against pediatric Crohn's disease.
BACKGROUND The IL-23 receptor (IL-23R) has been found to be associated with small bowel Crohn's disease (CD) in a whole genome… (More)
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Highly Cited
2006
Highly Cited
2006
Transforming growth factor-beta induces development of the T(H)17 lineage.
A new lineage of effector CD4+ T cells characterized by production of interleukin (IL)-17, the T-helper-17 (T(H)17) lineage, was… (More)
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Highly Cited
2006
Highly Cited
2006
Transforming growth factor-β induces development of the TH17 lineage
A new lineage of effector CD4+ T cells characterized by production of interleukin (IL)-17, the T-helper-17 (TH17) lineage, was… (More)
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