interleukin-22

Known as: Zcyto18, IL-22, Cytokine Zcyto18 
Interleukin-22 (179 aa, ~20 kDa) is encoded by the human IL22 gene. This protein is involved in both cell signaling and the immune response.
National Institutes of Health

Papers overview

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Highly Cited
2015
Highly Cited
2015
Epithelial regeneration is critical for barrier maintenance and organ function after intestinal injury. The intestinal stem cell… (More)
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Highly Cited
2013
Highly Cited
2013
Endogenous tryptophan (Trp) metabolites have an important role in mammalian gut immune homeostasis, yet the potential… (More)
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Highly Cited
2012
Highly Cited
2012
Endogenous thymic regeneration is a crucial function that allows for renewal of immune competence after stress, infection, or… (More)
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Highly Cited
2009
Highly Cited
2009
Natural killer (NK) cells are classically viewed as lymphocytes that provide innate surveillance against virally infected cells… (More)
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Review
2009
Review
2009
Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22… (More)
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Highly Cited
2008
Highly Cited
2008
Infections by attaching and effacing (A/E) bacterial pathogens, such as Escherichia coli O157:H7, pose a serious threat to public… (More)
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Highly Cited
2008
Highly Cited
2008
Natural killer (NK) cells are innate lymphocytes with spontaneous antitumor activity, and they produce interferon-gamma (IFN… (More)
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Highly Cited
2008
Highly Cited
2008
Emerging evidence supports the concept that T helper type 17 (TH17) cells, in addition to mediating autoimmunity, have key roles… (More)
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Highly Cited
2007
Highly Cited
2007
The cytokine interleukin-22 (IL-22) is primarily expressed by T helper 17 (Th17) CD4(+) T cells and is highly upregulated during… (More)
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Highly Cited
2004
Highly Cited
2004
The central role of T cell activation in hepatocellular injury has been well documented. In this article, we provide evidence… (More)
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