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integrator complex

Known as: integrator complex location 
A protein complex that stably associates with the C-terminus of RNA polymerase II and mediates 3'-end processing of small nuclear RNAs generated by… 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2020
Review
2020
Re-recognition of pseudogenes: From molecular to clinical applications
Pseudogenes were initially regarded as “nonfunctional” genomic elements that did not have protein-coding abilities due to several… 
2017
2017
Preliminary study on plasma proteins in pregnant and non-pregnant female dogs.
2015
2015
Pseudogene integrator complex subunit 6 pseudogene 1 (INTS6P1) as a novel plasma-based biomarker for hepatocellular carcinoma screening
In this study, we aimed to determine whether the pseudogene integrator complex subunit 6 pseudogene 1 (INTS6P1) in plasma could… 
2013
2013
A core hSSB1–INTS complex participates in the DNA damage response
Summary Human single-stranded DNA-binding protein 1 (hSSB1) plays an important role in the DNA damage response and the… 
2013
2013
Functional Analysis of the Integrator Subunit 12 Identifies a Microdomain That Mediates Activation of the Drosophila Integrator Complex*
Background: Small nuclear RNA (snRNA) 3′ end processing is carried out by the poorly understood integrator complex. Results: An… 
Highly Cited
2013
Highly Cited
2013
GSTCD and INTS12 Regulation and Expression in the Human Lung
Genome-Wide Association Study (GWAS) meta-analyses have identified a strong association signal for lung function, which maps to a… 
Highly Cited
2012
Highly Cited
2012
Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes
2012
2012
The integrator complex is required for integrity of Cajal bodies
The nucleus in eukaryotic cells is a highly organized and dynamic structure containing numerous subnuclear bodies. The… 
2007
2007
Targeted disruption of the murine large nuclear KIAA1440/Ints1 protein causes growth arrest in early blastocyst stage embryos and eventual apoptotic cell death.
Highly Cited
1999
Highly Cited
1999
Transcriptional activation by NF-kappaB requires multiple coactivators.
Nuclear factor-kappaB (NF-kappaB) plays a role in the transcriptional regulation of genes involved in inflammation and cell… 
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