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insulin detemir

Known as: Des-(B30)-insulin, Lys(B29)-tetradecanoyl, Detemir, B29 tetradecanoyl Lys B30 des Ala insulin 
A recombinant long-acting insulin and HYPOGLYCEMIC AGENT in which a MYRISTIC ACID is conjugated to a LYSINE at position B29. It is used to manage… 
National Institutes of Health

Related topics

Related topics

10 relations
3 ML insulin detemir 100 UNT/ML Pen Injector [Levemir]In Bloodanalogs & derivativesaspects of radiation effects

Broader (1)

Hypoglycemic Agents

Narrower (2)

LevemirNN304

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2007
Highly Cited
2007
A 26-Week, Randomized, Parallel, Treat-to-Target Trial Comparing Insulin Detemir With NPH Insulin as Add-On Therapy to Oral Glucose-Lowering Drugs in Insulin-Naïve People With Type 2 Diabetes
Review
2006
Review
2006
Insulin detemir: from concept to clinical experience
Insulin detemir (Levemir®, Novo Nordisk) is a novel, biologically engineered analogue of human insulin that has been successfully… 
Highly Cited
2005
Highly Cited
2005
Lower within‐subject variability of fasting blood glucose and reduced weight gain with insulin detemir compared to NPH insulin in patients with type 2 diabetes
Aim:  The aim of this study was to compare the efficacy and safety of a basal‐bolus insulin regimen comprising either insulin… 
Highly Cited
2004
Highly Cited
2004
Insulin analogues (insulin detemir and insulin aspart) versus traditional human insulins (NPH insulin and regular human insulin) in basal-bolus therapy for patients with Type 1 diabetes
Aims/hypothesisThe aim of the trial was to compare the efficacy and tolerability of two types of basal-bolus therapy, using… 
Highly Cited
2004
Highly Cited
2004
Insulin detemir offers improved glycemic control compared with NPH insulin in people with type 1 diabetes: a randomized clinical trial.
OBJECTIVE Insulin detemir is a soluble long-acting basal insulin analog designed to overcome the limitations of conventional… 
Highly Cited
1996
Highly Cited
1996
Regulation of p21WAF1/CIP1 expression by p53-independent pathways.
The CDK-inhibitor p21WAF1/CIP1 has been implicated as a growth arrest mediator in p53-tumour suppression, cellular senescence and… 
Highly Cited
1994
Highly Cited
1994
Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
SH-PTP2 is a nontransmembrane human protein-tyrosine phosphatase that contains two Src homology 2 (SH2) domains and binds to… 
Highly Cited
1987
Highly Cited
1987
Calcitonin gene-related peptide and muscle activity regulate acetylcholine receptor alpha-subunit mRNA levels by distinct intracellular pathways
In cultured chicken myotubes, calcitonin gene-related peptide (CGRP), a peptide present in spinal cord motoneurons, increased by… 
Highly Cited
1986
Highly Cited
1986
Potential role of activated macrophages in acetaminophen hepatotoxicity. I. Isolation and characterization of activated macrophages from rat liver.
Highly Cited
1983
Highly Cited
1983
Inhibition of the calcium- and phospholipid-dependent protein kinase activity from mouse brain cytosol by quercetin.
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